440275


Homo sapiens (NCBI)

Features
Gene ID: 440275
  
Biological name :
  
Synonyms : EIF2AK4 / eukaryotic translation initiation factor 2 alpha kinase 4 / GCN2|PVOD2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 225164_s_at (Human Genome U133 Plus 2.0 Array)   237145_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016877708.1
RefSeq - 530405872
RefSeq - 65287717
RefSeq - 767984234
RefSeq - 767984236
RefSeq - NC_000015.10
RefSeq - NG_034053.1
RefSeq - NP_001013725.2
RefSeq - XP_005254449.1
RefSeq - XP_011519901.1
RefSeq - XP_011519902.1
RefSeq - 1034590700
RefSeq - NM_001013703.3
RefSeq - XM_017022219.2
RefSeq - XM_005254392.3
RefSeq - XM_011521599.2
RefSeq - XM_011521600.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000128829 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IEA
 biological_processGO:0002230 positive regulation of defense response to virus by host ISS
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002286 T cell activation involved in immune response ISS
 biological_processGO:0002821 positive regulation of adaptive immune response ISS
 biological_processGO:0006446 regulation of translational initiation ISS
 biological_processGO:0006468 protein phosphorylation ISS
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0007612 learning ISS
 biological_processGO:0007616 long-term memory ISS
 biological_processGO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation ISS
 biological_processGO:0019081 viral translation ISS
 biological_processGO:0032057 negative regulation of translational initiation in response to stress ISS
 biological_processGO:0032792 negative regulation of CREB transcription factor activity ISS
 biological_processGO:0034198 cellular response to amino acid starvation ISS
 biological_processGO:0034644 cellular response to UV ISS
 biological_processGO:0036492 eiF2alpha phosphorylation in response to endoplasmic reticulum stress IMP
 biological_processGO:0039520 induction by virus of host autophagy ISS
 biological_processGO:0044828 negative regulation by host of viral genome replication ISS
 biological_processGO:0045665 negative regulation of neuron differentiation ISS
 biological_processGO:0045947 negative regulation of translational initiation ISS
 biological_processGO:0046777 protein autophosphorylation ISS
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060259 regulation of feeding behavior ISS
 biological_processGO:0060733 regulation of eIF2 alpha phosphorylation by amino acid starvation ISS
 biological_processGO:0070417 cellular response to cold IMP
 biological_processGO:0071264 positive regulation of translational initiation in response to starvation ISS
 biological_processGO:1900273 positive regulation of long-term synaptic potentiation ISS
 biological_processGO:1990138 neuron projection extension ISS
 biological_processGO:1990253 cellular response to leucine starvation ISS
 cellular_componentGO:0005844 polysome ISS
 cellular_componentGO:0022626 cytosolic ribosome ISS
 molecular_functionGO:0000049 tRNA binding ISS
 molecular_functionGO:0004672 protein kinase activity IBA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISS
 molecular_functionGO:0004694 eukaryotic translation initiation factor 2alpha kinase activity ISS
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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