4522


Homo sapiens (NCBI)

Features
Gene ID: 4522
  
Biological name :
  
Synonyms : CIMAH|MTHFC|MTHFD / methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 / MTHFD1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202309_at (Human Genome U133 Plus 2.0 Array)   239846_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 222136639
RefSeq - NC_000014.9
RefSeq - NG_012450.1
RefSeq - NP_005947.3
RefSeq - NM_005956.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000100714 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000105 histidine biosynthetic process IEA
 biological_processGO:0001780 neutrophil homeostasis IEA
 biological_processGO:0001843 neural tube closure ISS
 biological_processGO:0006164 purine nucleotide biosynthetic process ISS
 biological_processGO:0006555 methionine metabolic process ISS
 biological_processGO:0006730 one-carbon metabolic process IMP
 biological_processGO:0007507 heart development ISS
 biological_processGO:0009069 serine family amino acid metabolic process ISS
 biological_processGO:0009070 serine family amino acid biosynthetic process IMP
 biological_processGO:0009086 methionine biosynthetic process IMP
 biological_processGO:0009113 purine nucleobase biosynthetic process IBA
 biological_processGO:0009257 10-formyltetrahydrofolate biosynthetic process ISS
 biological_processGO:0019346 transsulfuration IEA
 biological_processGO:0035999 tetrahydrofolate interconversion ISS
 biological_processGO:0046655 folic acid metabolic process TAS
 biological_processGO:0048702 embryonic neurocranium morphogenesis ISS
 biological_processGO:0048703 embryonic viscerocranium morphogenesis ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0061053 somite development ISS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004329 formate-tetrahydrofolate ligase activity TAS
 molecular_functionGO:0004477 methenyltetrahydrofolate cyclohydrolase activity TAS
 molecular_functionGO:0004486 methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity TAS
 molecular_functionGO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity ISS
 molecular_functionGO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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