4792


Homo sapiens (NCBI)

Features
Gene ID: 4792
  
Biological name :
  
Synonyms : IKBA|MAD-3|NFKBI / NFKBIA / NFKB inhibitor alpha
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 201502_s_at (Human Genome U133 Plus 2.0 Array)   231699_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 10092619
RefSeq - NC_000014.9
RefSeq - NG_007571.1
RefSeq - NP_065390.1
RefSeq - NM_020529.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000100906 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000060 protein import into nucleus, translocation IEA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0007253 cytoplasmic sequestering of NF-kappaB IMP
 biological_processGO:0010745 negative regulation of macrophage derived foam cell differentiation IMP
 biological_processGO:0010875 positive regulation of cholesterol efflux IMP
 biological_processGO:0010888 negative regulation of lipid storage IMP
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0032270 positive regulation of cellular protein metabolic process IMP
 biological_processGO:0032495 response to muramyl dipeptide IEA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IDA
 biological_processGO:0034142 toll-like receptor 4 signaling pathway IEA
 biological_processGO:0035994 response to muscle stretch IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042994 cytoplasmic sequestering of transcription factor IDA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043330 response to exogenous dsRNA IEA
 biological_processGO:0043392 negative regulation of DNA binding NAS
 biological_processGO:0045638 negative regulation of myeloid cell differentiation IEA
 biological_processGO:0045746 negative regulation of Notch signaling pathway IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0050729 positive regulation of inflammatory response IDA
 biological_processGO:0070417 cellular response to cold NAS
 biological_processGO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway IEA
 biological_processGO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway IEA
 biological_processGO:0070498 interleukin-1-mediated signaling pathway TAS
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 biological_processGO:0097421 liver regeneration IEA
 biological_processGO:1901222 regulation of NIK/NF-kappaB signaling NAS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0033256 I-kappaB/NF-kappaB complex TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding TAS
 molecular_functionGO:0008139 nuclear localization sequence binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0051059 NF-kappaB binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr