4838


Homo sapiens (NCBI)

Features
Gene ID: 4838
  
Biological name :
  
Synonyms : HTX5 / NODAL / nodal growth differentiation factor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 230916_at (Human Genome U133 Plus 2.0 Array)   237896_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1049480183
RefSeq - 1370457174
RefSeq - 222352098
RefSeq - NC_000010.11
RefSeq - NG_012448.2
RefSeq - NP_001316835.1
RefSeq - NP_060525.3
RefSeq - XP_024303796.1
RefSeq - NM_001329906.1
RefSeq - NM_018055.4
RefSeq - XM_024448028.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000156574 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001831 trophectodermal cellular morphogenesis IEA
 biological_processGO:0001842 neural fold formation IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0001890 placenta development IMP
 biological_processGO:0001892 embryonic placenta development IEA
 biological_processGO:0001893 maternal placenta development IEA
 biological_processGO:0001944 vasculature development IEA
 biological_processGO:0001947 heart looping IEA
 biological_processGO:0002085 inhibition of neuroepithelial cell differentiation IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0009880 embryonic pattern specification IEA
 biological_processGO:0010085 polarity specification of proximal/distal axis IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010470 regulation of gastrulation IEA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production IMP
 biological_processGO:0010721 negative regulation of cell development IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IMP
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0022409 positive regulation of cell-cell adhesion IMP
 biological_processGO:0030509 BMP signaling pathway IBA
 biological_processGO:0032927 positive regulation of activin receptor signaling pathway IGI
 biological_processGO:0033505 floor plate morphogenesis IEA
 biological_processGO:0035987 endodermal cell differentiation IMP
 biological_processGO:0042074 cell migration involved in gastrulation IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048327 axial mesodermal cell fate specification IEA
 biological_processGO:0048382 mesendoderm development IMP
 biological_processGO:0048468 cell development IBA
 biological_processGO:0048546 digestive tract morphogenesis IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IEA
 biological_processGO:0048859 formation of anatomical boundary IEA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IDA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0060136 embryonic process involved in female pregnancy IEA
 biological_processGO:0060137 maternal process involved in parturition IEA
 biological_processGO:0060391 positive regulation of SMAD protein signal transduction IMP
 biological_processGO:0060395 SMAD protein signal transduction IBA
 biological_processGO:0060460 left lung morphogenesis IEA
 biological_processGO:0060766 negative regulation of androgen receptor signaling pathway IDA
 biological_processGO:0060802 epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0090010 transforming growth factor beta receptor signaling pathway involved in primitive streak formation IEA
 biological_processGO:1900164 nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry IEA
 biological_processGO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry ISS
 biological_processGO:1901164 negative regulation of trophoblast cell migration IDA
 biological_processGO:1901383 negative regulation of chorionic trophoblast cell proliferation IDA
 biological_processGO:2000036 regulation of stem cell population maintenance TAS
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0016015 morphogen activity NAS
 molecular_functionGO:0070698 type I activin receptor binding IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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