Manteia

4851

Homo sapiens (NCBI)

Features

Gene ID:	4851

Biological name :

Synonyms :	AOS5\|AOVD1\|TAN1\|hN1 / NOTCH1

Possible biological names infered from orthology :

Species:	Homo sapiens (NCBI)

Chr. number:
Strand:
Band:
Gene start:
Gene end:

Corresponding Affymetrix probe sets:	218902_at (Human Genome U133 Plus 2.0 Array) 223508_at (Human Genome U133 Plus 2.0 Array)

Cross references:	RefSeq - 1034665364 RefSeq - 148833508 RefSeq - NC_000009.12 RefSeq - NG_007458.1 RefSeq - NP_060087.3 RefSeq - XP_011517019.2 RefSeq - NM_017617.5 RefSeq - XM_011518717.2

See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000148400 to get all the annotations available for this gene.

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISS
biological_process	GO:0001701	in utero embryonic development	IEA
biological_process	GO:0001708	cell fate specification	IEA
biological_process	GO:0001837	epithelial to mesenchymal transition	ISS
biological_process	GO:0001889	liver development	IEA
biological_process	GO:0001947	heart looping	ISS
biological_process	GO:0002040	sprouting angiogenesis	IEA
biological_process	GO:0002052	positive regulation of neuroblast proliferation	IEA
biological_process	GO:0002437	inflammatory response to antigenic stimulus	IEA
biological_process	GO:0003151	outflow tract morphogenesis	IMP
biological_process	GO:0003157	endocardium development	ISS
biological_process	GO:0003160	endocardium morphogenesis	ISS
biological_process	GO:0003162	atrioventricular node development	IEA
biological_process	GO:0003169	coronary vein morphogenesis	ISS
biological_process	GO:0003180	aortic valve morphogenesis	TAS
biological_process	GO:0003181	atrioventricular valve morphogenesis	ISS
biological_process	GO:0003182	coronary sinus valve morphogenesis	IEA
biological_process	GO:0003184	pulmonary valve morphogenesis	ISS
biological_process	GO:0003192	mitral valve formation	IMP
biological_process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	ISS
biological_process	GO:0003203	endocardial cushion morphogenesis	ISS
biological_process	GO:0003207	cardiac chamber formation	ISS
biological_process	GO:0003208	cardiac ventricle morphogenesis	ISS
biological_process	GO:0003209	cardiac atrium morphogenesis	ISS
biological_process	GO:0003213	cardiac right atrium morphogenesis	ISS
biological_process	GO:0003214	cardiac left ventricle morphogenesis	ISS
biological_process	GO:0003219	cardiac right ventricle formation	IEA
biological_process	GO:0003222	ventricular trabecula myocardium morphogenesis	ISS
biological_process	GO:0003241	growth involved in heart morphogenesis	ISS
biological_process	GO:0003252	negative regulation of cell proliferation involved in heart valve morphogenesis	ISS
biological_process	GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	ISS
biological_process	GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	IEA
biological_process	GO:0003273	cell migration involved in endocardial cushion formation	ISS
biological_process	GO:0003332	negative regulation of extracellular matrix constituent secretion	ISS
biological_process	GO:0003344	pericardium morphogenesis	ISS
biological_process	GO:0006355	regulation of transcription, DNA-templated	TAS
biological_process	GO:0006367	transcription initiation from RNA polymerase II promoter	TAS
biological_process	GO:0006955	immune response	NAS
biological_process	GO:0006959	humoral immune response	IEA
biological_process	GO:0007050	cell cycle arrest	IDA
biological_process	GO:0007219	Notch signaling pathway	TAS
biological_process	GO:0007221	positive regulation of transcription of Notch receptor target	TAS
biological_process	GO:0007283	spermatogenesis	IEA
biological_process	GO:0007368	determination of left/right symmetry	ISS
biological_process	GO:0007386	compartment pattern specification	IEA
biological_process	GO:0007409	axonogenesis	IEA
biological_process	GO:0007440	foregut morphogenesis	IEA
biological_process	GO:0007492	endoderm development	IEA
biological_process	GO:0007507	heart development	IMP
biological_process	GO:0008284	positive regulation of cell proliferation	IMP
biological_process	GO:0008285	negative regulation of cell proliferation	IDA
biological_process	GO:0009912	auditory receptor cell fate commitment	IEA
biological_process	GO:0010614	negative regulation of cardiac muscle hypertrophy	ISS
biological_process	GO:0010628	positive regulation of gene expression	ISS
biological_process	GO:0010629	negative regulation of gene expression	IDA
biological_process	GO:0010718	positive regulation of epithelial to mesenchymal transition	IMP
biological_process	GO:0010812	negative regulation of cell-substrate adhesion	IDA
biological_process	GO:0010832	negative regulation of myotube differentiation	ISS
biological_process	GO:0014031	mesenchymal cell development	ISS
biological_process	GO:0014807	regulation of somitogenesis	IEA
biological_process	GO:0021515	cell differentiation in spinal cord	IEA
biological_process	GO:0021915	neural tube development	IEA
biological_process	GO:0030216	keratinocyte differentiation	IEA
biological_process	GO:0030279	negative regulation of ossification	ISS
biological_process	GO:0030324	lung development	IEA
biological_process	GO:0030335	positive regulation of cell migration	ISS
biological_process	GO:0030513	positive regulation of BMP signaling pathway	ISS
biological_process	GO:0030514	negative regulation of BMP signaling pathway	ISS
biological_process	GO:0030900	forebrain development	IEA
biological_process	GO:0031069	hair follicle morphogenesis	IEA
biological_process	GO:0031100	animal organ regeneration	IEA
biological_process	GO:0031960	response to corticosteroid	IEA
biological_process	GO:0032495	response to muramyl dipeptide	IEA
biological_process	GO:0032496	response to lipopolysaccharide	IEA
biological_process	GO:0035116	embryonic hindlimb morphogenesis	IEA
biological_process	GO:0035148	tube formation	IMP
biological_process	GO:0035914	skeletal muscle cell differentiation	IEA
biological_process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	IDA
biological_process	GO:0042246	tissue regeneration	IEA
biological_process	GO:0043086	negative regulation of catalytic activity	ISS
biological_process	GO:0045070	positive regulation of viral genome replication	IEA
biological_process	GO:0045603	positive regulation of endothelial cell differentiation	IEA
biological_process	GO:0045608	negative regulation of inner ear auditory receptor cell differentiation	IEA
biological_process	GO:0045618	positive regulation of keratinocyte differentiation	IEA
biological_process	GO:0045662	negative regulation of myoblast differentiation	IMP
biological_process	GO:0045668	negative regulation of osteoblast differentiation	ISS
biological_process	GO:0045747	positive regulation of Notch signaling pathway	TAS
biological_process	GO:0045892	negative regulation of transcription, DNA-templated	ISS
biological_process	GO:0045893	positive regulation of transcription, DNA-templated	ISS
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISS
biological_process	GO:0045955	negative regulation of calcium ion-dependent exocytosis	IEA
biological_process	GO:0045967	negative regulation of growth rate	IDA
biological_process	GO:0046427	positive regulation of JAK-STAT cascade	ISS
biological_process	GO:0046533	negative regulation of photoreceptor cell differentiation	IEA
biological_process	GO:0046579	positive regulation of Ras protein signal transduction	IDA
biological_process	GO:0048103	somatic stem cell division	IEA
biological_process	GO:0048708	astrocyte differentiation	IEA
biological_process	GO:0048709	oligodendrocyte differentiation	IEA
biological_process	GO:0048711	positive regulation of astrocyte differentiation	ISS
biological_process	GO:0048715	negative regulation of oligodendrocyte differentiation	ISS
biological_process	GO:0048754	branching morphogenesis of an epithelial tube	IEA
biological_process	GO:0048873	homeostasis of number of cells within a tissue	IEA
biological_process	GO:0050679	positive regulation of epithelial cell proliferation	IEA
biological_process	GO:0050768	negative regulation of neurogenesis	ISS
biological_process	GO:0055008	cardiac muscle tissue morphogenesis	ISS
biological_process	GO:0060038	cardiac muscle cell proliferation	IEA
biological_process	GO:0060045	positive regulation of cardiac muscle cell proliferation	ISS
biological_process	GO:0060253	negative regulation of glial cell proliferation	ISS
biological_process	GO:0060271	cilium assembly	ISS
biological_process	GO:0060317	cardiac epithelial to mesenchymal transition	ISS
biological_process	GO:0060411	cardiac septum morphogenesis	ISS
biological_process	GO:0060412	ventricular septum morphogenesis	IMP
biological_process	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	IEA
biological_process	GO:0060740	prostate gland epithelium morphogenesis	IEA
biological_process	GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	IEA
biological_process	GO:0060842	arterial endothelial cell differentiation	ISS
biological_process	GO:0060843	venous endothelial cell differentiation	ISS
biological_process	GO:0060948	cardiac vascular smooth muscle cell development	ISS
biological_process	GO:0060956	endocardial cell differentiation	ISS
biological_process	GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	ISS
biological_process	GO:0060982	coronary artery morphogenesis	ISS
biological_process	GO:0061314	Notch signaling involved in heart development	IMP
biological_process	GO:0061384	heart trabecula morphogenesis	ISS
biological_process	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	ISS
biological_process	GO:0070168	negative regulation of biomineral tissue development	ISS
biological_process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IDA
biological_process	GO:0070986	left/right axis specification	IEA
biological_process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	IDA
biological_process	GO:0072017	distal tubule development	IEA
biological_process	GO:0072044	collecting duct development	IEA
biological_process	GO:0072144	glomerular mesangial cell development	IEA
biological_process	GO:0072602	interleukin-4 secretion	IEA
biological_process	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	IDA
biological_process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IEA
biological_process	GO:0097150	neuronal stem cell population maintenance	IEP
biological_process	GO:1901201	regulation of extracellular matrix assembly	ISS
biological_process	GO:1902263	apoptotic process involved in embryonic digit morphogenesis	IEA
biological_process	GO:1902339	positive regulation of apoptotic process involved in morphogenesis	ISS
biological_process	GO:1903849	positive regulation of aorta morphogenesis	IEA
biological_process	GO:2000737	negative regulation of stem cell differentiation	IMP
biological_process	GO:2000811	negative regulation of anoikis	IMP
biological_process	GO:2000974	negative regulation of pro-B cell differentiation	ISS
biological_process	GO:2001027	negative regulation of endothelial cell chemotaxis	IDA
cellular_component	GO:0000139	Golgi membrane	TAS
cellular_component	GO:0001669	acrosomal vesicle	IEA
cellular_component	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex	IDA
cellular_component	GO:0005576	extracellular region	TAS
cellular_component	GO:0005634	nucleus	TAS
cellular_component	GO:0005654	nucleoplasm	TAS
cellular_component	GO:0005789	endoplasmic reticulum membrane	TAS
cellular_component	GO:0005829	cytosol	TAS
cellular_component	GO:0005886	plasma membrane	TAS
cellular_component	GO:0005912	adherens junction	ISS
cellular_component	GO:0009986	cell surface	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0016324	apical plasma membrane	ISS
cellular_component	GO:0043235	receptor complex	IDA
molecular_function	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	ISS
molecular_function	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding	ISS
molecular_function	GO:0003700	DNA-binding transcription factor activity	IEA
molecular_function	GO:0004857	enzyme inhibitor activity	ISS
molecular_function	GO:0004888	transmembrane signaling receptor activity	IEA
molecular_function	GO:0005112	Notch binding	IEA
molecular_function	GO:0005509	calcium ion binding	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0019899	enzyme binding	ISS
molecular_function	GO:0031490	chromatin DNA binding	IEA
molecular_function	GO:0046982	protein heterodimerization activity	IEA

Pathways (from Reactome)

Pathway description

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr