4914


Homo sapiens (NCBI)

Features
Gene ID: 4914
  
Biological name :
  
Synonyms : MTC|TRK|TRK1|TRKA|Trk-A|p140-TrkA / neurotrophic receptor tyrosine kinase 1 / NTRK1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208605_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4585712
RefSeq - 56118210
RefSeq - 59889558
RefSeq - NC_000001.11
RefSeq - NG_007493.1
RefSeq - NP_001007793.1
RefSeq - NP_001012331.1
RefSeq - NP_002520.2
RefSeq - NM_001007792.1
RefSeq - NM_001012331.1
RefSeq - NM_002529.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000198400 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000186 activation of MAPKK activity TAS
 biological_processGO:0001934 positive regulation of protein phosphorylation TAS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0009314 response to radiation IEA
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010623 programmed cell death involved in cell development ISS
 biological_processGO:0010976 positive regulation of neuron projection development IDA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0021553 olfactory nerve development IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030183 B cell differentiation IEA
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IMP
 biological_processGO:0038180 nerve growth factor signaling pathway IMP
 biological_processGO:0042490 mechanoreceptor differentiation IEA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043068 positive regulation of programmed cell death ISS
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISS
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 biological_processGO:0046579 positive regulation of Ras protein signal transduction IDA
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048011 neurotrophin TRK receptor signaling pathway TAS
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling TAS
 biological_processGO:0048485 sympathetic nervous system development ISS
 biological_processGO:0048678 response to axon injury IEA
 biological_processGO:0050965 detection of temperature stimulus involved in sensory perception of pain IEA
 biological_processGO:0050966 detection of mechanical stimulus involved in sensory perception of pain IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0051599 response to hydrostatic pressure IEA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0051968 positive regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0060009 Sertoli cell development IEA
 biological_processGO:0060385 axonogenesis involved in innervation ISS
 biological_processGO:0061368 behavioral response to formalin induced pain IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:0071316 cellular response to nicotine IEA
 biological_processGO:1904646 cellular response to amyloid-beta IDA
 biological_processGO:1990090 cellular response to nerve growth factor stimulus ISS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005768 endosome TAS
 cellular_componentGO:0005769 early endosome ISS
 cellular_componentGO:0005770 late endosome ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0032991 protein-containing complex ISS
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IDA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IMP
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005004 GPI-linked ephrin receptor activity IEA
 molecular_functionGO:0005030 neurotrophin receptor activity IBA
 molecular_functionGO:0005166 neurotrophin p75 receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0010465 nerve growth factor receptor activity IMP
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043121 neurotrophin binding TAS
 molecular_functionGO:0048406 nerve growth factor binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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