4915


Homo sapiens (NCBI)

Features
Gene ID: 4915
  
Biological name :
  
Synonyms : EIEE58|GP145-TrkB|OBHD|TRKB|trk-B / neurotrophic receptor tyrosine kinase 2 / NTRK2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207152_at (Human Genome U133 Plus 2.0 Array)   214680_at (Human Genome U133 Plus 2.0 Array)   221795_at (Human Genome U133 Plus 2.0 Array)   221796_at (Human Genome U133 Plus 2.0 Array)   229463_at (Human Genome U133 Plus 2.0 Array)   236095_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 633257777
RefSeq - 1034665390
RefSeq - 1034665392
RefSeq - 1034665394
RefSeq - 1034665397
RefSeq - 1034665399
RefSeq - 1034665402
RefSeq - 1034665405
RefSeq - 1034665407
RefSeq - 1034665409
RefSeq - 1034665411
RefSeq - 21361306
RefSeq - 530391141
RefSeq - 530391145
RefSeq - 530391147
RefSeq - 530391151
RefSeq - 530391153
RefSeq - 55956790
RefSeq - 1034665386
RefSeq - 65506745
RefSeq - 65506769
RefSeq - 65506779
RefSeq - 767957532
RefSeq - 767957536
RefSeq - NC_000009.12
RefSeq - NG_012201.2
RefSeq - NP_001007098.1
RefSeq - NP_001018074.1
RefSeq - NP_001018075.1
RefSeq - NP_001018076.1
RefSeq - NP_001278866.1
RefSeq - NP_006171.2
RefSeq - XP_005252058.1
RefSeq - XP_005252060.1
RefSeq - XP_005252061.1
RefSeq - XP_005252063.1
RefSeq - XP_005252064.1
RefSeq - XP_011517020.1
RefSeq - XP_011517022.1
RefSeq - XP_016870240.1
RefSeq - XP_016870241.1
RefSeq - XP_016870242.1
RefSeq - XP_016870243.1
RefSeq - XP_016870244.1
RefSeq - XP_016870245.1
RefSeq - XP_016870246.1
RefSeq - XP_016870247.1
RefSeq - XP_016870248.1
RefSeq - XP_016870249.1
RefSeq - XP_016870250.1
RefSeq - NM_001007097.2
RefSeq - NM_001018064.2
RefSeq - NM_001018065.2
RefSeq - NM_001018066.2
RefSeq - NM_001291937.1
RefSeq - NM_006180.4
RefSeq - XM_017014756.1
RefSeq - XM_017014757.1
RefSeq - XM_017014758.1
RefSeq - XM_017014759.1
RefSeq - XM_017014760.2
RefSeq - XM_017014761.1
RefSeq - XM_005252001.3
RefSeq - XM_005252003.3
RefSeq - XM_005252004.2
RefSeq - XM_005252006.4
RefSeq - XM_005252007.4
RefSeq - XM_011518718.3
RefSeq - XM_011518720.3
RefSeq - XM_017014751.2
RefSeq - XM_017014752.1
RefSeq - XM_017014753.2
RefSeq - XM_017014754.1
RefSeq - XM_017014755.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000148053 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001764 neuron migration ISS
 biological_processGO:0001934 positive regulation of protein phosphorylation TAS
 biological_processGO:0007202 activation of phospholipase C activity TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007528 neuromuscular junction development IEA
 biological_processGO:0007612 learning ISS
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0007631 feeding behavior IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0010976 positive regulation of neuron projection development ISS
 biological_processGO:0014047 glutamate secretion IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISS
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0021954 central nervous system neuron development ISS
 biological_processGO:0021987 cerebral cortex development ISS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0031547 brain-derived neurotrophic factor receptor signaling pathway TAS
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0042490 mechanoreceptor differentiation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043087 regulation of GTPase activity ISS
 biological_processGO:0043410 positive regulation of MAPK cascade ISS
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISS
 biological_processGO:0046548 retinal rod cell development IEA
 biological_processGO:0046777 protein autophosphorylation ISS
 biological_processGO:0048011 neurotrophin TRK receptor signaling pathway TAS
 biological_processGO:0048709 oligodendrocyte differentiation IEA
 biological_processGO:0048935 peripheral nervous system neuron development IEA
 biological_processGO:0050772 positive regulation of axonogenesis ISS
 biological_processGO:0051896 regulation of protein kinase B signaling IEA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0060291 long-term synaptic potentiation IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 biological_processGO:0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission IEA
 biological_processGO:1903997 positive regulation of non-membrane spanning protein tyrosine kinase activity TAS
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IBA
 biological_processGO:2000811 negative regulation of anoikis IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005769 early endosome ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0030424 axon IBA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0043197 dendritic spine IBA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0043679 axon terminus IBA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005030 neurotrophin receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0043121 neurotrophin binding ISS
 molecular_functionGO:0048403 brain-derived neurotrophic factor binding ISS
 molecular_functionGO:0060175 brain-derived neurotrophic factor-activated receptor activity IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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