5027


Homo sapiens (NCBI)

Features
Gene ID: 5027
  
Biological name :
  
Synonyms : P2RX7 / P2X7 / purinergic receptor P2X 7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207091_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034579767
RefSeq - 1034579769
RefSeq - 1034579771
RefSeq - 1034579773
RefSeq - 300068987
RefSeq - 767974441
RefSeq - 767974443
RefSeq - NC_000012.12
RefSeq - NG_011471.2
RefSeq - NP_002553.3
RefSeq - XP_011536721.1
RefSeq - XP_011536722.1
RefSeq - XP_016874853.1
RefSeq - XP_016874854.1
RefSeq - XP_016874855.1
RefSeq - XP_016874856.1
RefSeq - NR_033952.1
RefSeq - NR_033953.1
RefSeq - NR_033954.1
RefSeq - NR_033955.1
RefSeq - NR_033956.1
RefSeq - XM_011538419.3
RefSeq - XM_011538420.3
RefSeq - XM_017019364.2
RefSeq - XM_017019365.2
RefSeq - XM_017019366.2
RefSeq - NM_002562.5
RefSeq - NM_177427.2
RefSeq - XM_017019367.2
RefSeq - NR_033948.1
RefSeq - NR_033949.1
RefSeq - NR_033950.1
RefSeq - NR_033951.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000089041 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0001845 phagolysosome assembly IEA
 biological_processGO:0001916 positive regulation of T cell mediated cytotoxicity IEA
 biological_processGO:0002028 regulation of sodium ion transport ISS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006509 membrane protein ectodomain proteolysis IEA
 biological_processGO:0006649 phospholipid transfer to membrane IEA
 biological_processGO:0006812 cation transport IBA
 biological_processGO:0006900 vesicle budding from membrane IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0007166 cell surface receptor signaling pathway ISS
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0010043 response to zinc ion IEA
 biological_processGO:0010524 positive regulation of calcium ion transport into cytosol IDA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0014049 positive regulation of glutamate secretion IEA
 biological_processGO:0014054 positive regulation of gamma-aminobutyric acid secretion IEA
 biological_processGO:0016079 synaptic vesicle exocytosis IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0017121 phospholipid scrambling IDA
 biological_processGO:0019233 sensory perception of pain ISS
 biological_processGO:0019835 cytolysis IEA
 biological_processGO:0030163 protein catabolic process IEA
 biological_processGO:0030501 positive regulation of bone mineralization ISS
 biological_processGO:0031668 cellular response to extracellular stimulus IEA
 biological_processGO:0032060 bleb assembly ISS
 biological_processGO:0032308 positive regulation of prostaglandin secretion IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0032963 collagen metabolic process IEA
 biological_processGO:0033198 response to ATP IDA
 biological_processGO:0034220 ion transmembrane transport IBA
 biological_processGO:0034405 response to fluid shear stress IEA
 biological_processGO:0034767 positive regulation of ion transmembrane transport IMP
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway IMP
 biological_processGO:0042098 T cell proliferation IEA
 biological_processGO:0043029 T cell homeostasis IEA
 biological_processGO:0043132 NAD transport IEA
 biological_processGO:0043409 negative regulation of MAPK cascade ISS
 biological_processGO:0045332 phospholipid translocation IEA
 biological_processGO:0045779 negative regulation of bone resorption ISS
 biological_processGO:0045794 negative regulation of cell volume IMP
 biological_processGO:0045821 positive regulation of glycolytic process IMP
 biological_processGO:0045919 positive regulation of cytolysis ISS
 biological_processGO:0046513 ceramide biosynthetic process IEA
 biological_processGO:0046931 pore complex assembly IMP
 biological_processGO:0048705 skeletal system morphogenesis IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0050717 positive regulation of interleukin-1 alpha secretion IEA
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion IDA
 biological_processGO:0050830 defense response to Gram-positive bacterium IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0051495 positive regulation of cytoskeleton organization ISS
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0051709 regulation of killing of cells of other organism NAS
 biological_processGO:0051899 membrane depolarization IDA
 biological_processGO:0051901 positive regulation of mitochondrial depolarization IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0070230 positive regulation of lymphocyte apoptotic process IEA
 biological_processGO:0071359 cellular response to dsRNA IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:0097190 apoptotic signaling pathway ISS
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:1904172 positive regulation of bleb assembly IMP
 cellular_componentGO:0005639 integral component of nuclear inner membrane IBA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IC
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0031594 neuromuscular junction IEA
 cellular_componentGO:0032059 bleb ISS
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0098793 presynapse IEA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0001530 lipopolysaccharide binding ISS
 molecular_functionGO:0001614 purinergic nucleotide receptor activity IDA
 molecular_functionGO:0004931 extracellularly ATP-gated cation channel activity TAS
 molecular_functionGO:0005102 signaling receptor binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IC
 molecular_functionGO:0035381 ATP-gated ion channel activity IBA
 molecular_functionGO:0042803 protein homodimerization activity NAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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