5054


Homo sapiens (NCBI)

Features
Gene ID: 5054
  
Biological name :
  
Synonyms : PAI|PAI-1|PAI1|PLANH1 / SERPINE1 / serpin family E member 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1568765_at (Human Genome U133 Plus 2.0 Array)   202627_s_at (Human Genome U133 Plus 2.0 Array)   202628_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 10835159
RefSeq - NC_000007.14
RefSeq - NG_013213.1
RefSeq - NP_000593.1
RefSeq - NM_000602.4
RefSeq - NM_001165413.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000106366 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001300 chronological cell aging IEP
 biological_processGO:0001525 angiogenesis IEP
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0007623 circadian rhythm TAS
 biological_processGO:0010469 regulation of signaling receptor activity IDA
 biological_processGO:0010757 negative regulation of plasminogen activation IMP
 biological_processGO:0010951 negative regulation of endopeptidase activity IDA
 biological_processGO:0014912 negative regulation of smooth muscle cell migration IDA
 biological_processGO:0030194 positive regulation of blood coagulation IMP
 biological_processGO:0030195 negative regulation of blood coagulation IC
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0032757 positive regulation of interleukin-8 production IMP
 biological_processGO:0033629 negative regulation of cell adhesion mediated by integrin IDA
 biological_processGO:0035491 positive regulation of leukotriene production involved in inflammatory response IMP
 biological_processGO:0042730 fibrinolysis TAS
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II TAS
 biological_processGO:0048260 positive regulation of receptor-mediated endocytosis IDA
 biological_processGO:0050729 positive regulation of inflammatory response IGI
 biological_processGO:0050829 defense response to Gram-negative bacterium IGI
 biological_processGO:0051918 negative regulation of fibrinolysis IDA
 biological_processGO:0061044 negative regulation of vascular wound healing IGI
 biological_processGO:0061045 negative regulation of wound healing IC
 biological_processGO:0071222 cellular response to lipopolysaccharide IMP
 biological_processGO:0071277 cellular response to calcium ion HEP
 biological_processGO:0090026 positive regulation of monocyte chemotaxis IMP
 biological_processGO:0090399 replicative senescence IMP
 biological_processGO:0097187 dentinogenesis IDA
 biological_processGO:1901331 positive regulation of odontoblast differentiation IDA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IMP
 biological_processGO:2000098 negative regulation of smooth muscle cell-matrix adhesion IDA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 cellular_componentGO:0062023 collagen-containing extracellular matrix IDA
 cellular_componentGO:0070062 extracellular exosome IDA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity TAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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