50943


Homo sapiens (NCBI)

Features
Gene ID: 50943
  
Biological name :
  
Synonyms : AIID|DIETER|IPEX|JM2|PIDX|XPID / forkhead box P3 / FOXP3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 221333_at (Human Genome U133 Plus 2.0 Array)   221334_s_at (Human Genome U133 Plus 2.0 Array)   224211_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034674457
RefSeq - 167466190
RefSeq - 31982943
RefSeq - 768033199
RefSeq - NC_000023.11
RefSeq - NG_007392.1
RefSeq - NP_001107849.1
RefSeq - NP_054728.2
RefSeq - XP_006724596.2
RefSeq - XP_016885056.1
RefSeq - NM_001114377.1
RefSeq - NM_014009.3
RefSeq - XM_006724533.2
RefSeq - XM_017029567.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000049768 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001782 B cell homeostasis IEA
 biological_processGO:0001816 cytokine production IEA
 biological_processGO:0002262 myeloid cell homeostasis IEA
 biological_processGO:0002362 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment TAS
 biological_processGO:0002456 T cell mediated immunity IEA
 biological_processGO:0002513 tolerance induction to self antigen IEA
 biological_processGO:0002667 regulation of T cell anergy ISS
 biological_processGO:0002669 positive regulation of T cell anergy IEA
 biological_processGO:0002677 negative regulation of chronic inflammatory response IEA
 biological_processGO:0002725 negative regulation of T cell cytokine production IMP
 biological_processGO:0002851 positive regulation of peripheral T cell tolerance induction IEA
 biological_processGO:0006338 chromatin remodeling NAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0009615 response to virus IEP
 biological_processGO:0030111 regulation of Wnt signaling pathway TAS
 biological_processGO:0031064 negative regulation of histone deacetylation IGI
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0032689 negative regulation of interferon-gamma production IMP
 biological_processGO:0032693 negative regulation of interleukin-10 production IDA
 biological_processGO:0032700 negative regulation of interleukin-17 production IMP
 biological_processGO:0032703 negative regulation of interleukin-2 production IMP
 biological_processGO:0032713 negative regulation of interleukin-4 production IDA
 biological_processGO:0032714 negative regulation of interleukin-5 production IEA
 biological_processGO:0032715 negative regulation of interleukin-6 production IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production IEA
 biological_processGO:0032792 negative regulation of CREB transcription factor activity IDA
 biological_processGO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation TAS
 biological_processGO:0032914 positive regulation of transforming growth factor beta1 production IEA
 biological_processGO:0033092 positive regulation of immature T cell proliferation in thymus IEA
 biological_processGO:0035066 positive regulation of histone acetylation IMP
 biological_processGO:0035067 negative regulation of histone acetylation IEA
 biological_processGO:0042036 negative regulation of cytokine biosynthetic process IDA
 biological_processGO:0042110 T cell activation IDA
 biological_processGO:0042130 negative regulation of T cell proliferation IMP
 biological_processGO:0043029 T cell homeostasis NAS
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0045077 negative regulation of interferon-gamma biosynthetic process IEA
 biological_processGO:0045085 negative regulation of interleukin-2 biosynthetic process IMP
 biological_processGO:0045589 regulation of regulatory T cell differentiation TAS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0046007 negative regulation of activated T cell proliferation NAS
 biological_processGO:0048294 negative regulation of isotype switching to IgE isotypes IEA
 biological_processGO:0048302 regulation of isotype switching to IgG isotypes IEA
 biological_processGO:0050710 negative regulation of cytokine secretion IDA
 biological_processGO:0050777 negative regulation of immune response IDA
 biological_processGO:0050852 T cell receptor signaling pathway IEA
 biological_processGO:2000320 negative regulation of T-helper 17 cell differentiation IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0032991 protein-containing complex NAS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISS
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IMP
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035035 histone acetyltransferase binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051059 NF-kappaB binding NAS
 molecular_functionGO:0051525 NFAT protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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