5155


Homo sapiens (NCBI)

Features
Gene ID: 5155
  
Biological name :
  
Synonyms : IBGC5|PDGF-2|PDGF2|SIS|SSV|c-sis / PDGFB / platelet derived growth factor subunit B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204200_s_at (Human Genome U133 Plus 2.0 Array)   216055_at (Human Genome U133 Plus 2.0 Array)   216061_x_at (Human Genome U133 Plus 2.0 Array)   217112_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 15451786
RefSeq - 4505681
RefSeq - NC_000022.11
RefSeq - NG_012111.1
RefSeq - NP_002599.1
RefSeq - NP_148937.1
RefSeq - NM_002608.3
RefSeq - NM_033016.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000100311 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001892 embryonic placenta development ISS
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IDA
 biological_processGO:0002548 monocyte chemotaxis IDA
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0003104 positive regulation of glomerular filtration ISS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0007507 heart development ISS
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0009611 response to wounding NAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010512 negative regulation of phosphatidylinositol biosynthetic process IDA
 biological_processGO:0010544 negative regulation of platelet activation IDA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0014911 positive regulation of smooth muscle cell migration IDA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IDA
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0032147 activation of protein kinase activity IDA
 biological_processGO:0032148 activation of protein kinase B activity IDA
 biological_processGO:0035655 interleukin-18-mediated signaling pathway IDA
 biological_processGO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway IDA
 biological_processGO:0038001 paracrine signaling ISS
 biological_processGO:0043406 positive regulation of MAP kinase activity IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IDA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IDA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IDA
 biological_processGO:0045840 positive regulation of mitotic nuclear division IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IDA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IDA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IDA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0050921 positive regulation of chemotaxis IDA
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060326 cell chemotaxis IDA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IDA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:0070528 protein kinase C signaling IMP
 biological_processGO:0071363 cellular response to growth factor stimulus IDA
 biological_processGO:0071506 cellular response to mycophenolic acid ISS
 biological_processGO:0072126 positive regulation of glomerular mesangial cell proliferation IDA
 biological_processGO:0072255 metanephric glomerular mesangial cell development ISS
 biological_processGO:0072593 reactive oxygen species metabolic process IMP
 biological_processGO:0090280 positive regulation of calcium ion import IDA
 biological_processGO:1900127 positive regulation of hyaluronan biosynthetic process IDA
 biological_processGO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II IDA
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IDA
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IDA
 biological_processGO:1904754 positive regulation of vascular associated smooth muscle cell migration IDA
 biological_processGO:1905064 negative regulation of vascular smooth muscle cell differentiation IDA
 biological_processGO:1905176 positive regulation of vascular smooth muscle cell dedifferentiation IDA
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IDA
 biological_processGO:2000573 positive regulation of DNA biosynthetic process IDA
 biological_processGO:2000591 positive regulation of metanephric mesenchymal cell migration IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016323 basolateral plasma membrane ISS
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 cellular_componentGO:0062023 collagen-containing extracellular matrix HDA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005518 collagen binding IDA
 molecular_functionGO:0008083 growth factor activity IDA
 molecular_functionGO:0016176 superoxide-generating NADPH oxidase activator activity IDA
 molecular_functionGO:0042056 chemoattractant activity IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0048407 platelet-derived growth factor binding IPI
 molecular_functionGO:0070851 growth factor receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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