5156


Homo sapiens (NCBI)

Features
Gene ID: 5156
  
Biological name :
  
Synonyms : CD140A|PDGFR-2|PDGFR2 / PDGFRA / platelet derived growth factor receptor alpha
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1554828_at (Human Genome U133 Plus 2.0 Array)   203131_at (Human Genome U133 Plus 2.0 Array)   211533_at (Human Genome U133 Plus 2.0 Array)   215305_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034640093
RefSeq - 1115538439
RefSeq - 1115538444
RefSeq - 1115538446
RefSeq - 1115538448
RefSeq - 530376789
RefSeq - 5453870
RefSeq - 578808641
RefSeq - NC_000004.12
RefSeq - NG_009250.1
RefSeq - NP_001334756.1
RefSeq - NP_001334757.1
RefSeq - NP_001334758.1
RefSeq - NP_001334759.1
RefSeq - NP_006197.1
RefSeq - XP_005265800.1
RefSeq - XP_006714104.1
RefSeq - XP_016863770.1
RefSeq - NM_001347827.1
RefSeq - NM_001347828.1
RefSeq - NM_001347829.1
RefSeq - NM_001347830.1
RefSeq - NM_006206.5
RefSeq - XM_006714041.3
RefSeq - XM_017008281.1
RefSeq - XM_005265743.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000134853 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001553 luteinization ISS
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001775 cell activation TAS
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IMP
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008210 estrogen metabolic process IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010544 negative regulation of platelet activation IDA
 biological_processGO:0010863 positive regulation of phospholipase C activity IMP
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030325 adrenal gland development IEA
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0030539 male genitalia development IEA
 biological_processGO:0033327 Leydig cell differentiation IEA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0034614 cellular response to reactive oxygen species IDA
 biological_processGO:0035790 platelet-derived growth factor receptor-alpha signaling pathway IMP
 biological_processGO:0038091 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway IDA
 biological_processGO:0042060 wound healing ISS
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IDA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IMP
 biological_processGO:0048146 positive regulation of fibroblast proliferation IDA
 biological_processGO:0048557 embryonic digestive tract morphogenesis ISS
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis ISS
 biological_processGO:0048704 embryonic skeletal system morphogenesis ISS
 biological_processGO:0050920 regulation of chemotaxis IMP
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0055003 cardiac myofibril assembly ISS
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0060325 face morphogenesis IEA
 biological_processGO:0060326 cell chemotaxis IMP
 biological_processGO:0061298 retina vasculature development in camera-type eye ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070527 platelet aggregation IMP
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 biological_processGO:0072277 metanephric glomerular capillary formation ISS
 biological_processGO:2000249 regulation of actin cytoskeleton reorganization TAS
 biological_processGO:2000739 regulation of mesenchymal stem cell differentiation IMP
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005018 platelet-derived growth factor alpha-receptor activity IMP
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity IDA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038085 vascular endothelial growth factor binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0048407 platelet-derived growth factor binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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