5159


Homo sapiens (NCBI)

Features
Gene ID: 5159
  
Biological name :
  
Synonyms : CD140B|IBGC4|IMF1|JTK12|KOGS|PDGFR|PDGFR-1|PDGFR1|PENTT / PDGFRB / platelet derived growth factor receptor beta
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202273_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001341945.1
RefSeq - NP_001341946.1
RefSeq - NP_002600.1
RefSeq - 1239396133
RefSeq - NG_023367.1
RefSeq - 1239396136
RefSeq - 4505683
RefSeq - NC_000005.10
RefSeq - NR_149150.1
RefSeq - NM_001355016.1
RefSeq - NM_001355017.1
RefSeq - NM_002609.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000113721 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0006024 glycosaminoglycan biosynthetic process IEA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007568 aging IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010863 positive regulation of phospholipase C activity IDA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISS
 biological_processGO:0014911 positive regulation of smooth muscle cell migration ISS
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032516 positive regulation of phosphoprotein phosphatase activity IDA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization ISS
 biological_processGO:0032967 positive regulation of collagen biosynthetic process IEA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0034405 response to fluid shear stress IEA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IEA
 biological_processGO:0035441 cell migration involved in vasculogenesis ISS
 biological_processGO:0035789 metanephric mesenchymal cell migration IEA
 biological_processGO:0035791 platelet-derived growth factor receptor-beta signaling pathway IMP
 biological_processGO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway ISS
 biological_processGO:0035909 aorta morphogenesis ISS
 biological_processGO:0036120 cellular response to platelet-derived growth factor stimulus IEA
 biological_processGO:0038091 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway IDA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043406 positive regulation of MAP kinase activity ISS
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IDA
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045840 positive regulation of mitotic nuclear division ISS
 biological_processGO:0046488 phosphatidylinositol metabolic process IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IDA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IMP
 biological_processGO:0048146 positive regulation of fibroblast proliferation IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISS
 biological_processGO:0048839 inner ear development IEA
 biological_processGO:0050921 positive regulation of chemotaxis ISS
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0055003 cardiac myofibril assembly ISS
 biological_processGO:0055093 response to hyperoxia IEA
 biological_processGO:0060326 cell chemotaxis IDA
 biological_processGO:0060437 lung growth IEA
 biological_processGO:0060981 cell migration involved in coronary angiogenesis ISS
 biological_processGO:0061298 retina vasculature development in camera-type eye ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0071670 smooth muscle cell chemotaxis ISS
 biological_processGO:0072075 metanephric mesenchyme development IEA
 biological_processGO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development ISS
 biological_processGO:0072277 metanephric glomerular capillary formation ISS
 biological_processGO:0072278 metanephric comma-shaped body morphogenesis IEA
 biological_processGO:0072284 metanephric S-shaped body morphogenesis IEA
 biological_processGO:0090280 positive regulation of calcium ion import ISS
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process ISS
 biological_processGO:2000491 positive regulation of hepatic stellate cell activation IEA
 biological_processGO:2000573 positive regulation of DNA biosynthetic process ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043202 lysosomal lumen IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IDA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0004992 platelet activating factor receptor activity TAS
 molecular_functionGO:0005017 platelet-derived growth factor-activated receptor activity TAS
 molecular_functionGO:0005019 platelet-derived growth factor beta-receptor activity IMP
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038085 vascular endothelial growth factor binding IPI
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IEA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0048407 platelet-derived growth factor binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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