5170


Homo sapiens (NCBI)

Features
Gene ID: 5170
  
Biological name :
  
Synonyms : 3-phosphoinositide dependent protein kinase 1 / PDK1|PDPK2|PDPK2P|PRO0461 / PDPK1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204524_at (Human Genome U133 Plus 2.0 Array)   221244_s_at (Human Genome U133 Plus 2.0 Array)   224986_s_at (Human Genome U133 Plus 2.0 Array)   244629_s_at (Human Genome U133 Plus 2.0 Array)   244630_at (Human Genome U133 Plus 2.0 Array)   32029_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4505695
RefSeq - 1034594750
RefSeq - 1034594752
RefSeq - 1034594754
RefSeq - 1034594756
RefSeq - 1034594759
RefSeq - 1034594761
RefSeq - 1370468544
RefSeq - 1370468546
RefSeq - 387849239
RefSeq - 1034594747
RefSeq - 47680169
RefSeq - 767987287
RefSeq - 767987291
RefSeq - NC_000016.10
RefSeq - NP_001248745.1
RefSeq - NP_002604.1
RefSeq - NP_112558.2
RefSeq - XP_011520823.1
RefSeq - XP_011520825.1
RefSeq - XP_016878760.1
RefSeq - XP_016878761.1
RefSeq - XP_016878762.1
RefSeq - XP_016878763.1
RefSeq - XP_016878764.1
RefSeq - XP_016878765.1
RefSeq - XP_016878766.1
RefSeq - XP_024306063.1
RefSeq - XP_024306064.1
RefSeq - NM_001261816.1
RefSeq - NM_002613.4
RefSeq - NM_031268.5
RefSeq - XM_017023277.1
RefSeq - XM_024450295.1
RefSeq - XM_024450296.1
RefSeq - XM_011522521.3
RefSeq - XM_011522523.3
RefSeq - XM_017023271.2
RefSeq - XM_017023272.2
RefSeq - XM_017023273.2
RefSeq - XM_017023274.1
RefSeq - XM_017023275.2
RefSeq - XM_017023276.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000140992 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0003323 type B pancreatic cell development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006469 negative regulation of protein kinase activity IDA
 biological_processGO:0006972 hyperosmotic response IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IMP
 biological_processGO:0010518 positive regulation of phospholipase activity IMP
 biological_processGO:0010667 negative regulation of cardiac muscle cell apoptotic process IEA
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0019722 calcium-mediated signaling IMP
 biological_processGO:0030036 actin cytoskeleton organization TAS
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0031295 T cell costimulation TAS
 biological_processGO:0032148 activation of protein kinase B activity TAS
 biological_processGO:0032869 cellular response to insulin stimulus IMP
 biological_processGO:0034122 negative regulation of toll-like receptor signaling pathway IEA
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0043304 regulation of mast cell degranulation IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IMP
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0046777 protein autophosphorylation TAS
 biological_processGO:0048041 focal adhesion assembly IEA
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IDA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IMP
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IMP
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IMP
 biological_processGO:1903672 positive regulation of sprouting angiogenesis IMP
 biological_processGO:1905564 positive regulation of vascular endothelial cell proliferation IMP
 biological_processGO:1990416 cellular response to brain-derived neurotrophic factor stimulus IEA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IMP
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042995 cell projection IDA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004676 3-phosphoinositide-dependent protein kinase activity IDA
 molecular_functionGO:0005158 insulin receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016004 phospholipase activator activity IMP
 molecular_functionGO:0016301 kinase activity TAS
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0043274 phospholipase binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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