5290


Homo sapiens (NCBI)

Features
Gene ID: 5290
  
Biological name :
  
Synonyms : CLOVE|CWS5|MCAP|MCM|MCMTC|PI3K|PI3K-alpha|p110-alpha / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha / PIK3CA
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204369_at (Human Genome U133 Plus 2.0 Array)   231854_at (Human Genome U133 Plus 2.0 Array)   235980_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 54792082
RefSeq - 578807473
RefSeq - 767926912
RefSeq - NC_000003.12
RefSeq - NG_012113.2
RefSeq - NP_006209.2
RefSeq - XP_006713721.1
RefSeq - XP_011511196.1
RefSeq - NM_006218.3
RefSeq - XM_011512894.2
RefSeq - XM_006713658.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000121879 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0001944 vasculature development TAS
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling IBA
 biological_processGO:0016242 negative regulation of macroautophagy NAS
 biological_processGO:0016310 phosphorylation IDA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0031295 T cell costimulation TAS
 biological_processGO:0032008 positive regulation of TOR signaling NAS
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase TAS
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0038128 ERBB2 signaling pathway TAS
 biological_processGO:0040014 regulation of multicellular organism growth IEA
 biological_processGO:0043276 anoikis NAS
 biological_processGO:0043457 regulation of cellular respiration IEA
 biological_processGO:0043491 protein kinase B signaling IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0043542 endothelial cell migration TAS
 biological_processGO:0044029 hypomethylation of CpG island IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation ISS
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048015 phosphatidylinositol-mediated signaling TAS
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060048 cardiac muscle contraction TAS
 biological_processGO:0060612 adipose tissue development IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0097009 energy homeostasis IEA
 biological_processGO:2000270 negative regulation of fibroblast apoptotic process IEA
 biological_processGO:2000653 regulation of genetic imprinting IEA
 biological_processGO:2000811 negative regulation of anoikis IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005942 phosphatidylinositol 3-kinase complex ISS
 cellular_componentGO:0005943 phosphatidylinositol 3-kinase complex, class IA IDA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0030027 lamellipodium IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity TAS
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0030295 protein kinase activator activity IEA
 molecular_functionGO:0035004 phosphatidylinositol 3-kinase activity TAS
 molecular_functionGO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity IBA
 molecular_functionGO:0043560 insulin receptor substrate binding IEA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0052742 phosphatidylinositol kinase activity IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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