5295


Homo sapiens (NCBI)

Features
Gene ID: 5295
  
Biological name :
  
Synonyms : AGM7|GRB1|IMD36|p85|p85-ALPHA / phosphoinositide-3-kinase regulatory subunit 1 / PIK3R1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 212239_at (Human Genome U133 Plus 2.0 Array)   212240_s_at (Human Genome U133 Plus 2.0 Array)   212249_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034645286
RefSeq - 1034645288
RefSeq - 32455248
RefSeq - 32455250
RefSeq - 32455252
RefSeq - 335057534
RefSeq - 530379378
RefSeq - 767936139
RefSeq - NC_000005.10
RefSeq - NG_012849.2
RefSeq - NP_001229395.1
RefSeq - NP_852556.2
RefSeq - NP_852664.1
RefSeq - NP_852665.1
RefSeq - XP_005248599.1
RefSeq - XP_011541795.1
RefSeq - XP_016865074.1
RefSeq - XP_016865075.1
RefSeq - NM_001242466.1
RefSeq - NM_181504.3
RefSeq - NM_181523.2
RefSeq - NM_181524.1
RefSeq - XM_005248542.3
RefSeq - XM_011543493.3
RefSeq - XM_017009585.2
RefSeq - XM_017009586.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000145675 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001678 cellular glucose homeostasis ISS
 biological_processGO:0001953 negative regulation of cell-matrix adhesion IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0008286 insulin receptor signaling pathway IBA
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling IMP
 biological_processGO:0016032 viral process IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030183 B cell differentiation IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0031295 T cell costimulation TAS
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IEA
 biological_processGO:0032869 cellular response to insulin stimulus ISS
 biological_processGO:0033120 positive regulation of RNA splicing IMP
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress ISS
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0038128 ERBB2 signaling pathway TAS
 biological_processGO:0042307 positive regulation of protein import into nucleus IDA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043551 regulation of phosphatidylinositol 3-kinase activity ISS
 biological_processGO:0045671 negative regulation of osteoclast differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0046326 positive regulation of glucose import ISS
 biological_processGO:0046626 regulation of insulin receptor signaling pathway IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation ISS
 biological_processGO:0048009 insulin-like growth factor receptor signaling pathway IPI
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048015 phosphatidylinositol-mediated signaling TAS
 biological_processGO:0050821 protein stabilization IDA
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051492 regulation of stress fiber assembly IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060396 growth hormone receptor signaling pathway IDA
 biological_processGO:1900103 positive regulation of endoplasmic reticulum unfolded protein response IMP
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane ISS
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005801 cis-Golgi network IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005942 phosphatidylinositol 3-kinase complex ISS
 cellular_componentGO:0005943 phosphatidylinositol 3-kinase complex, class IA ISS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:1990578 perinuclear endoplasmic reticulum membrane IEA
 molecular_functionGO:0001784 phosphotyrosine residue binding IPI
 molecular_functionGO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity ISS
 molecular_functionGO:0005158 insulin receptor binding IPI
 molecular_functionGO:0005159 insulin-like growth factor receptor binding IPI
 molecular_functionGO:0005168 neurotrophin TRKA receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0035014 phosphatidylinositol 3-kinase regulator activity ISS
 molecular_functionGO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding IEA
 molecular_functionGO:0043125 ErbB-3 class receptor binding IDA
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding ISS
 molecular_functionGO:0043559 insulin binding IDA
 molecular_functionGO:0043560 insulin receptor substrate binding ISS
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0046935 1-phosphatidylinositol-3-kinase regulator activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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