5311


Homo sapiens (NCBI)

Features
Gene ID: 5311
  
Biological name :
  
Synonyms : APKD2|PC2|PKD4|Pc-2|TRPP2 / PKD2 / polycystin 2, transient receptor potential cation channel
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203688_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NC_000004.12
RefSeq - NG_008604.1
RefSeq - XP_011530330.1
RefSeq - XP_011530331.1
RefSeq - XP_011530332.1
RefSeq - 4505835
RefSeq - 767932098
RefSeq - NP_000288.1
RefSeq - 767932100
RefSeq - 767932102
RefSeq - XR_001741236.2
RefSeq - NM_000297.3
RefSeq - NR_156488.1
RefSeq - XM_011532028.2
RefSeq - XM_011532029.1
RefSeq - XM_011532030.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000118762 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEP
 biological_processGO:0001889 liver development IEP
 biological_processGO:0001892 embryonic placenta development ISS
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0003127 detection of nodal flow ISS
 biological_processGO:0006816 calcium ion transport ISS
 biological_processGO:0007050 cell cycle arrest ISS
 biological_processGO:0007259 JAK-STAT cascade ISS
 biological_processGO:0007368 determination of left/right symmetry ISS
 biological_processGO:0007507 heart development IEP
 biological_processGO:0008285 negative regulation of cell proliferation NAS
 biological_processGO:0021510 spinal cord development IEP
 biological_processGO:0021915 neural tube development IEP
 biological_processGO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity IMP
 biological_processGO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle IDA
 biological_processGO:0034614 cellular response to reactive oxygen species NAS
 biological_processGO:0035502 metanephric part of ureteric bud development IEP
 biological_processGO:0035725 sodium ion transmembrane transport IMP
 biological_processGO:0035904 aorta development IEP
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0042994 cytoplasmic sequestering of transcription factor IMP
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0050982 detection of mechanical stimulus ISS
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IMP
 biological_processGO:0051289 protein homotetramerization IDA
 biological_processGO:0051298 centrosome duplication NAS
 biological_processGO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity ISS
 biological_processGO:0060674 placenta blood vessel development ISS
 biological_processGO:0061333 renal tubule morphogenesis ISS
 biological_processGO:0061441 renal artery morphogenesis IEP
 biological_processGO:0070588 calcium ion transmembrane transport IDA
 biological_processGO:0071158 positive regulation of cell cycle arrest IMP
 biological_processGO:0071277 cellular response to calcium ion ISS
 biological_processGO:0071320 cellular response to cAMP IMP
 biological_processGO:0071464 cellular response to hydrostatic pressure IDA
 biological_processGO:0071470 cellular response to osmotic stress IDA
 biological_processGO:0071498 cellular response to fluid shear stress IMP
 biological_processGO:0071805 potassium ion transmembrane transport ISS
 biological_processGO:0071910 determination of liver left/right asymmetry IMP
 biological_processGO:0072075 metanephric mesenchyme development IEP
 biological_processGO:0072164 mesonephric tubule development IEP
 biological_processGO:0072177 mesonephric duct development IEP
 biological_processGO:0072208 metanephric smooth muscle tissue development IEP
 biological_processGO:0072214 metanephric cortex development IEP
 biological_processGO:0072218 metanephric ascending thin limb development IEP
 biological_processGO:0072219 metanephric cortical collecting duct development IEP
 biological_processGO:0072235 metanephric distal tubule development IEP
 biological_processGO:0072284 metanephric S-shaped body morphogenesis IEP
 biological_processGO:0090279 regulation of calcium ion import IDA
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IMP
 cellular_componentGO:0002133 polycystin complex ISS
 cellular_componentGO:0005737 cytoplasm IMP
 cellular_componentGO:0005783 endoplasmic reticulum IMP
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IMP
 cellular_componentGO:0005911 cell-cell junction ISS
 cellular_componentGO:0005929 cilium ISS
 cellular_componentGO:0009925 basal plasma membrane IDA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031514 motile cilium ISS
 cellular_componentGO:0031941 filamentous actin IDA
 cellular_componentGO:0036064 ciliary basal body IDA
 cellular_componentGO:0045180 basal cortex IDA
 cellular_componentGO:0060170 ciliary membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane IDA
 cellular_componentGO:0071556 integral component of lumenal side of endoplasmic reticulum membrane IDA
 cellular_componentGO:0072686 mitotic spindle IDA
 cellular_componentGO:0097730 non-motile cilium ISS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005244 voltage-gated ion channel activity IDA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IDA
 molecular_functionGO:0005248 voltage-gated sodium channel activity IMP
 molecular_functionGO:0005249 voltage-gated potassium channel activity IMP
 molecular_functionGO:0005262 calcium channel activity IBA
 molecular_functionGO:0005267 potassium channel activity ISS
 molecular_functionGO:0005509 calcium ion binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008092 cytoskeletal protein binding IDA
 molecular_functionGO:0015271 outward rectifier potassium channel activity ISS
 molecular_functionGO:0022843 voltage-gated cation channel activity IDA
 molecular_functionGO:0042802 identical protein binding ISS
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0042805 actinin binding IDA
 molecular_functionGO:0043398 HLH domain binding IPI
 molecular_functionGO:0044325 ion channel binding IPI
 molecular_functionGO:0048763 calcium-induced calcium release activity IDA
 molecular_functionGO:0051117 ATPase binding ISS
 molecular_functionGO:0051219 phosphoprotein binding IPI
 molecular_functionGO:0051371 muscle alpha-actinin binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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