5371


Homo sapiens (NCBI)

Features
Gene ID: 5371
  
Biological name :
  
Synonyms : MYL|PP8675|RNF71|TRIM19 / PML / promyelocytic leukemia
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206503_x_at (Human Genome U133 Plus 2.0 Array)   209640_at (Human Genome U133 Plus 2.0 Array)   210362_x_at (Human Genome U133 Plus 2.0 Array)   211012_s_at (Human Genome U133 Plus 2.0 Array)   211013_x_at (Human Genome U133 Plus 2.0 Array)   211014_s_at (Human Genome U133 Plus 2.0 Array)   211588_s_at (Human Genome U133 Plus 2.0 Array)   211589_at (Human Genome U133 Plus 2.0 Array)   235508_at (Human Genome U133 Plus 2.0 Array)   239582_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 109637788
RefSeq - 15451765
RefSeq - 15451775
RefSeq - 15451779
RefSeq - 4505903
RefSeq - 67089149
RefSeq - 67089154
RefSeq - 67089157
RefSeq - 67089160
RefSeq - NC_000015.10
RefSeq - NG_029036.1
RefSeq - NP_002666.1
RefSeq - NP_150241.2
RefSeq - NP_150242.1
RefSeq - NP_150243.2
RefSeq - NP_150247.2
RefSeq - NP_150249.1
RefSeq - NP_150250.2
RefSeq - NP_150252.1
RefSeq - NP_150253.2
RefSeq - NM_002675.3
RefSeq - NM_033238.2
RefSeq - NM_033239.2
RefSeq - NM_033240.2
RefSeq - NM_033244.3
RefSeq - NM_033246.2
RefSeq - NM_033247.2
RefSeq - NM_033249.2
RefSeq - NM_033250.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000140464 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0001932 regulation of protein phosphorylation ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IMP
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest ISS
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0007182 common-partner SMAD protein phosphorylation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0010522 regulation of calcium ion transport into cytosol ISS
 biological_processGO:0010761 fibroblast migration IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016525 negative regulation of angiogenesis IMP
 biological_processGO:0030099 myeloid cell differentiation IEA
 biological_processGO:0030155 regulation of cell adhesion IEA
 biological_processGO:0030308 negative regulation of cell growth IDA
 biological_processGO:0030578 PML body organization IMP
 biological_processGO:0032206 positive regulation of telomere maintenance IMP
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis ISS
 biological_processGO:0032922 circadian regulation of gene expression ISS
 biological_processGO:0034097 response to cytokine IDA
 biological_processGO:0042752 regulation of circadian rhythm ISS
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISS
 biological_processGO:0043153 entrainment of circadian clock by photoperiod ISS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0045087 innate immune response IDA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045345 positive regulation of MHC class I biosynthetic process IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IEA
 biological_processGO:0048384 retinoic acid receptor signaling pathway IEA
 biological_processGO:0050713 negative regulation of interleukin-1 beta secretion IEA
 biological_processGO:0051457 maintenance of protein location in nucleus IDA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway TAS
 biological_processGO:0060444 branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0065003 protein-containing complex assembly IDA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
 biological_processGO:0071353 cellular response to interleukin-4 IEA
 biological_processGO:0090398 cellular senescence IDA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 biological_processGO:1902187 negative regulation of viral release from host cell IDA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 biological_processGO:2000059 negative regulation of ubiquitin-dependent protein catabolic process IMP
 biological_processGO:2000779 regulation of double-strand break repair IMP
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IDA
 cellular_componentGO:0000792 heterochromatin IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0016605 PML body TAS
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0042406 extrinsic component of endoplasmic reticulum membrane ISS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0032183 SUMO binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046332 SMAD binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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