5468


Homo sapiens (NCBI)

Features
Gene ID: 5468
  
Biological name :
  
Synonyms : CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma / peroxisome proliferator activated receptor gamma / PPARG
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208510_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 20336229
RefSeq - 116284368
RefSeq - 116284370
RefSeq - 116284373
RefSeq - 1233267478
RefSeq - 1233267490
RefSeq - 1233267520
RefSeq - 1233267549
RefSeq - 1237937951
RefSeq - 1370484449
RefSeq - 1370484451
RefSeq - 1370484453
RefSeq - 1060604690
RefSeq - 767923589
RefSeq - 767923591
RefSeq - 767923593
RefSeq - NC_000003.12
RefSeq - NG_011749.1
RefSeq - NP_001317544.1
RefSeq - NP_001341595.1
RefSeq - NP_001341596.1
RefSeq - NP_001341597.1
RefSeq - NP_001341598.1
RefSeq - NP_001341599.1
RefSeq - NP_005028.4
RefSeq - NP_056953.2
RefSeq - NP_619725.2
RefSeq - NP_619726.2
RefSeq - XP_011532144.1
RefSeq - XP_011532145.1
RefSeq - XP_011532146.1
RefSeq - XP_024309372.1
RefSeq - XP_024309373.1
RefSeq - XP_024309374.1
RefSeq - NM_001330615.1
RefSeq - NM_001354666.1
RefSeq - NM_001354667.1
RefSeq - NM_001354668.1
RefSeq - NM_001354669.1
RefSeq - NM_001354670.1
RefSeq - NM_005037.5
RefSeq - NM_015869.4
RefSeq - NM_138711.3
RefSeq - NM_138712.3
RefSeq - XM_011533844.1
RefSeq - XM_024453604.1
RefSeq - XM_024453605.1
RefSeq - XM_024453606.1
RefSeq - XM_011533842.2
RefSeq - XM_011533843.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000132170 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0001890 placenta development ISS
 biological_processGO:0002674 negative regulation of acute inflammatory response IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006629 lipid metabolic process TAS
 biological_processGO:0006631 fatty acid metabolic process IBA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007584 response to nutrient TAS
 biological_processGO:0008217 regulation of blood pressure IMP
 biological_processGO:0009409 response to cold IEA
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0009755 hormone-mediated signaling pathway IBA
 biological_processGO:0010742 macrophage derived foam cell differentiation IDA
 biological_processGO:0010745 negative regulation of macrophage derived foam cell differentiation IDA
 biological_processGO:0010871 negative regulation of receptor biosynthetic process IDA
 biological_processGO:0010887 negative regulation of cholesterol storage IDA
 biological_processGO:0010891 negative regulation of sequestering of triglyceride IDA
 biological_processGO:0015909 long-chain fatty acid transport ISS
 biological_processGO:0016525 negative regulation of angiogenesis IDA
 biological_processGO:0019216 regulation of lipid metabolic process IBA
 biological_processGO:0019395 fatty acid oxidation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030224 monocyte differentiation IDA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0030855 epithelial cell differentiation ISS
 biological_processGO:0031000 response to caffeine IEA
 biological_processGO:0031100 animal organ regeneration IEA
 biological_processGO:0031667 response to nutrient levels IBA
 biological_processGO:0032526 response to retinoic acid IDA
 biological_processGO:0032869 cellular response to insulin stimulus IMP
 biological_processGO:0032966 negative regulation of collagen biosynthetic process IEA
 biological_processGO:0033189 response to vitamin A IEA
 biological_processGO:0033993 response to lipid ISS
 biological_processGO:0035357 peroxisome proliferator activated receptor signaling pathway IMP
 biological_processGO:0035902 response to immobilization stress IEA
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0042594 response to starvation IEA
 biological_processGO:0042752 regulation of circadian rhythm ISS
 biological_processGO:0042953 lipoprotein transport IDA
 biological_processGO:0043388 positive regulation of DNA binding IMP
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0043537 negative regulation of blood vessel endothelial cell migration IDA
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0045165 cell fate commitment ISS
 biological_processGO:0045600 positive regulation of fat cell differentiation ISS
 biological_processGO:0045713 low-density lipoprotein particle receptor biosynthetic process IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045923 positive regulation of fatty acid metabolic process IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0046321 positive regulation of fatty acid oxidation IEA
 biological_processGO:0048469 cell maturation IDA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IDA
 biological_processGO:0048714 positive regulation of oligodendrocyte differentiation IEA
 biological_processGO:0050728 negative regulation of inflammatory response IBA
 biological_processGO:0050872 white fat cell differentiation TAS
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0051974 negative regulation of telomerase activity IEA
 biological_processGO:0055088 lipid homeostasis TAS
 biological_processGO:0060100 positive regulation of phagocytosis, engulfment IEA
 biological_processGO:0060336 negative regulation of interferon-gamma-mediated signaling pathway IMP
 biological_processGO:0060694 regulation of cholesterol transporter activity IC
 biological_processGO:0060850 regulation of transcription involved in cell fate commitment ISS
 biological_processGO:0060965 negative regulation of gene silencing by miRNA IMP
 biological_processGO:0061614 pri-miRNA transcription by RNA polymerase II IDA
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:0071306 cellular response to vitamin E IEA
 biological_processGO:0071380 cellular response to prostaglandin E stimulus IEA
 biological_processGO:0071396 cellular response to lipid IBA
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus IDA
 biological_processGO:0071455 cellular response to hyperoxia IEA
 biological_processGO:1901558 response to metformin IEA
 biological_processGO:1904706 negative regulation of vascular smooth muscle cell proliferation IMP
 biological_processGO:1905461 positive regulation of vascular associated smooth muscle cell apoptotic process IMP
 biological_processGO:1905563 negative regulation of vascular endothelial cell proliferation IMP
 biological_processGO:2000230 negative regulation of pancreatic stellate cell proliferation IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IDA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001103 RNA polymerase II repressing transcription factor binding IBA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0003682 chromatin binding ISS
 molecular_functionGO:0003690 double-stranded DNA binding IMP
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISS
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IDA
 molecular_functionGO:0004955 prostaglandin receptor activity TAS
 molecular_functionGO:0005504 fatty acid binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IDA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0008144 drug binding IDA
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0008289 lipid binding IBA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0030331 estrogen receptor binding IEA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IDA
 molecular_functionGO:0033613 activating transcription factor binding IDA
 molecular_functionGO:0042277 peptide binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0043621 protein self-association IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding ISS
 molecular_functionGO:0046965 retinoid X receptor binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0050544 arachidonic acid binding ISS
 molecular_functionGO:0050692 DBD domain binding IDA
 molecular_functionGO:0050693 LBD domain binding IDA
 molecular_functionGO:0051393 alpha-actinin binding IPI
 molecular_functionGO:0070888 E-box binding ISS
 molecular_functionGO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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