5538


Homo sapiens (NCBI)
processregulationproteinactivitycatabolicdevelopmentmembranehydrolasereceptor-mediatedendocytosispinocytosislysosomallumenbehaviortransportcellraftapoptoticneuroncofactorextracellulardepalmitoylationacidificationneurotransmittersecretionnervousbrainvisualperceptiongrooming

Features
Gene ID: 5538
  
Biological name :
  
Synonyms : CLN1|INCL|PPT / palmitoyl-protein thioesterase 1 / PPT1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 200975_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1391895289
RefSeq - 217272890
RefSeq - 4506031
RefSeq - 530362927
RefSeq - NC_000001.11
RefSeq - NG_009192.1
RefSeq - NP_000301.1
RefSeq - NP_001136076.1
RefSeq - NP_001350624.1
RefSeq - XP_005271065.1
RefSeq - NM_000310.3
RefSeq - NM_001142604.1
RefSeq - NM_001363695.1
RefSeq - XM_005271008.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000131238 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular component organizationregulation of biological qualitycell communicationcellular localizationanatomical structure developmentsystem processgrooming behaviorlocomotory behavioradult behaviormacromolecule localizationcell growthregulation of molecular functioncell deathbiosynthetic processsmall molecule metabolic processcellular developmental processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular component organizationregulation of biological qualitycell communicationcellular localizationanatomical structure developmentsystem processgrooming behaviorlocomotory behavioradult behaviormacromolecule localizationcell growthregulation of molecular functioncell deathbiosynthetic processsmall molecule metabolic processcellular developmental processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular component organizationregulation of biological qualitycell communicationcellular localizationanatomical structure developmentsystem processgrooming behaviorlocomotory behavioradult behaviormacromolecule localizationcell growthregulation of molecular functioncell deathbiosynthetic processsmall molecule metabolic processcellular developmental processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular component organizationregulation of biological qualitycell communicationcellular localizationanatomical structure developmentsystem processgrooming behaviorlocomotory behavioradult behaviormacromolecule localizationcell growthregulation of molecular functioncell deathbiosynthetic processsmall molecule metabolic processcellular developmental processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular component organizationregulation of biological qualitycell communicationcellular localizationanatomical structure developmentsystem processgrooming behaviorlocomotory behavioradult behaviormacromolecule localizationcell growthregulation of molecular functioncell deathbiosynthetic processsmall molecule metabolic processcellular developmental processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular component organizationregulation of biological qualitycell communicationcellular localizationanatomical structure developmentsystem processgrooming behaviorlocomotory behavioradult behaviormacromolecule localizationcell growthregulation of molecular functioncell deathbiosynthetic processsmall molecule metabolic processcellular developmental processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular component organizationregulation of biological qualitycell communicationcellular localizationanatomical structure developmentsystem processgrooming behaviorlocomotory behavioradult behaviormacromolecule localizationcell growthregulation of molecular functioncell deathbiosynthetic processsmall molecule metabolic processcellular developmental processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular component organizationregulation of biological qualitycell communicationcellular localizationanatomical structure developmentsystem processgrooming behaviorlocomotory behavioradult behaviormacromolecule localizationcell growthregulation of molecular functioncell deathbiosynthetic processsmall molecule metabolic processcellular developmental processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular component organizationregulation of biological qualitycell communicationcellular localizationanatomical structure developmentsystem processgrooming behaviorlocomotory behavioradult behaviormacromolecule localizationcell growthregulation of molecular functioncell deathbiosynthetic processsmall molecule metabolic processcellular developmental processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular component organizationregulation of biological qualitycell communicationcellular localizationanatomical structure developmentsystem processgrooming behaviorlocomotory behavioradult behaviormacromolecule localizationcell growthregulation of molecular functioncell deathbiosynthetic processsmall molecule metabolic processcellular developmental processnitrognitrogen compound metabolic processcatabocatabolic processcellulcellular metabolic processprimarprimary metabolic processorganiorganic substance metabolic processestablestablishment of localizationcellulcellular component organizationregularegulation of biological qualitycell ccell communicationcellulcellular localizationanatomanatomical structure developmentsystemsystem processgroomigrooming behaviorlocomolocomotory behavioradult adult behaviormacrommacromolecule localizationcell gcell growthregularegulation of molecular functioncell dcell deathbiosynbiosynthetic processsmall small molecule metabolic processcellulcellular developmental process
protein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingprotein bindingcatalytic activity, acting on a proteincatalytic activity, acting on a proteinhydrolase activityhydrolase activity
extracellular regioncellorganellesynapsemembranemembrane-enclosed lumenextracellular regioncellorganellesynapsemembranemembrane-enclosed lumenextracellular regioncellorganellesynapsemembranemembrane-enclosed lumenextracellular regioncellorganellesynapsemembranemembrane-enclosed lumenextracellular regioncellorganellesynapsemembranemembrane-enclosed lumenextracellular regioncellorganellesynapsemembranemembrane-enclosed lumenextracellular regioncellorganellesynapsemembranemembrane-enclosed lumenextracellular regioncellorganellesynapsemembranemembrane-enclosed lumenextracellular regioncellorganellesynapsemembranemembrane-enclosed lumenextracellular regioncellorganellesynapsemembranemembrane-enclosed lumenextracellular regionextracellular regioncellcellorganelleorganellesynapsesynapsemembranemembranemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0002084 protein depalmitoylation ISS
 biological_processGO:0006898 receptor-mediated endocytosis IMP
 biological_processGO:0006907 pinocytosis IMP
 biological_processGO:0007042 lysosomal lumen acidification IMP
 biological_processGO:0007269 neurotransmitter secretion IEA
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0007420 brain development IMP
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007625 grooming behavior IEA
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0015031 protein transport IMP
 biological_processGO:0016042 lipid catabolic process IDA
 biological_processGO:0030149 sphingolipid catabolic process TAS
 biological_processGO:0030163 protein catabolic process NAS
 biological_processGO:0030308 negative regulation of cell growth IMP
 biological_processGO:0031579 membrane raft organization IMP
 biological_processGO:0032429 regulation of phospholipase A2 activity IEA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:0044257 cellular protein catabolic process IEA
 biological_processGO:0046949 fatty-acyl-CoA biosynthetic process TAS
 biological_processGO:0048260 positive regulation of receptor-mediated endocytosis IMP
 biological_processGO:0048549 positive regulation of pinocytosis IMP
 biological_processGO:0048666 neuron development TAS
 biological_processGO:0050803 regulation of synapse structure or activity NAS
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0051181 cofactor transport IMP
 biological_processGO:0051186 cofactor metabolic process IMP
 cellular_componentGO:0005576 extracellular region ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005764 lysosome ISS
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0008021 synaptic vesicle IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043202 lysosomal lumen TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 cellular_componentGO:0045121 membrane raft IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008474 palmitoyl-(protein) hydrolase activity TAS
 molecular_functionGO:0016290 palmitoyl-CoA hydrolase activity ISS
 molecular_functionGO:0016790 thiolester hydrolase activity IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr