5552


Homo sapiens (NCBI)
granulesecretorycellorganizationmastplateletproteinregulationtmaintenancelocationextracellulardegranulationgranzyme-mediatedapoptoticsignalingpathwayprocessingbonemineralizationbiomineraltissuedevelopmentproteasegranzymebcytokinesecretionregionspace

Features
Gene ID: 5552
  
Biological name :
  
Synonyms : PPG|PRG|PRG1 / serglycin / SRGN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1554676_at (Human Genome U133 Plus 2.0 Array)   201858_s_at (Human Genome U133 Plus 2.0 Array)   201859_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_024303834.1
RefSeq - 1005261259
RefSeq - 1034568695
RefSeq - 1370457349
RefSeq - 1370457352
RefSeq - 1370457354
RefSeq - 45935371
RefSeq - NC_000010.11
RefSeq - NP_001307982.1
RefSeq - NP_001307983.1
RefSeq - NP_002718.2
RefSeq - XP_016871881.1
RefSeq - XP_024303832.1
RefSeq - XP_024303833.1
RefSeq - 1005261256
RefSeq - NM_001321053.1
RefSeq - NM_001321054.1
RefSeq - NM_002727.3
RefSeq - XM_024448064.1
RefSeq - XM_024448065.1
RefSeq - XM_024448066.1
RefSeq - XM_017016392.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000122862 to get all the annotations available for this gene.


Gene Ontology (GO)
establishment of localizationcell communicationcellular response to stimuluscell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentossificationcellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcytokine productionestablishment of localizationcell communicationcellular response to stimuluscell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentossificationcellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcytokine productionestablishment of localizationcell communicationcellular response to stimuluscell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentossificationcellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcytokine productionestablishment of localizationcell communicationcellular response to stimuluscell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentossificationcellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcytokine productionestablishment of localizationcell communicationcellular response to stimuluscell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentossificationcellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcytokine productionestablishment of localizationcell communicationcellular response to stimuluscell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentossificationcellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcytokine productionestablishment of localizationcell communicationcellular response to stimuluscell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentossificationcellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcytokine productionestablishment of localizationcell communicationcellular response to stimuluscell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentossificationcellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcytokine productionestablishment of localizationcell communicationcellular response to stimuluscell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentossificationcellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcytokine productionestablishment of localizationcell communicationcellular response to stimuluscell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentossificationcellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcytokine productionestablishmestablishment of localizationcell commucell communicationcellular rcellular response to stimuluscell deathcell deathnitrogen cnitrogen compound metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processanatomicalanatomical structure developmentossificatiossificationcellular ccellular component organizationmacromolecmacromolecule localizationregulationregulation of biological qualitycellular lcellular localizationcytokine pcytokine production
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
extracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regionextracellular regioncellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0008626 granzyme-mediated apoptotic signaling pathway IDA
 biological_processGO:0016485 protein processing ISS
 biological_processGO:0030502 negative regulation of bone mineralization IDA
 biological_processGO:0031214 biomineral tissue development IEA
 biological_processGO:0033363 secretory granule organization IBA
 biological_processGO:0033364 mast cell secretory granule organization ISS
 biological_processGO:0033371 T cell secretory granule organization ISS
 biological_processGO:0033373 maintenance of protease location in mast cell secretory granule ISS
 biological_processGO:0033382 maintenance of granzyme B location in T cell secretory granule ISS
 biological_processGO:0050710 negative regulation of cytokine secretion ISS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0030141 secretory granule IBA
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 cellular_componentGO:0042629 mast cell granule ISS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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