558


Homo sapiens (NCBI)

Features
Gene ID: 558
  
Biological name :
  
Synonyms : ARK|JTK11|Tyro7|UFO / AXL / AXL receptor tyrosine kinase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202685_s_at (Human Genome U133 Plus 2.0 Array)   202686_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 21536466
RefSeq - 21536468
RefSeq - 520260399
RefSeq - NC_000019.10
RefSeq - NP_001265528.1
RefSeq - NP_001690.2
RefSeq - NP_068713.2
RefSeq - NM_001278599.1
RefSeq - NM_001699.5
RefSeq - NM_021913.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000167601 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0001779 natural killer cell differentiation IEA
 biological_processGO:0001961 positive regulation of cytokine-mediated signaling pathway IDA
 biological_processGO:0001974 blood vessel remodeling IEA
 biological_processGO:0006909 phagocytosis IDA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0021885 forebrain cell migration IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030168 platelet activation IEA
 biological_processGO:0031100 animal organ regeneration IEA
 biological_processGO:0031668 cellular response to extracellular stimulus IEA
 biological_processGO:0032689 negative regulation of interferon-gamma production IDA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0032825 positive regulation of natural killer cell differentiation IDA
 biological_processGO:0032940 secretion by cell IEA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0034101 erythrocyte homeostasis IEA
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IEA
 biological_processGO:0035457 cellular response to interferon-alpha IDA
 biological_processGO:0042698 ovulation cycle IEA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043277 apoptotic cell clearance IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043491 protein kinase B signaling IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0046718 viral entry into host cell IMP
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048469 cell maturation IEP
 biological_processGO:0048549 positive regulation of pinocytosis IMP
 biological_processGO:0051250 negative regulation of lymphocyte activation IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:0060068 vagina development IEA
 biological_processGO:0070301 cellular response to hydrogen peroxide IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071222 cellular response to lipopolysaccharide IDA
 biological_processGO:0097028 dendritic cell differentiation IEP
 biological_processGO:0097350 neutrophil clearance IEA
 biological_processGO:2000669 negative regulation of dendritic cell apoptotic process IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0044228 host cell surface IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0001786 phosphatidylserine binding IDA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0017147 Wnt-protein binding IBA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0032036 myosin heavy chain binding IEA
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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