5591


Homo sapiens (NCBI)

Features
Gene ID: 5591
  
Biological name :
  
Synonyms : DNA-PKcs|DNAPK|DNPK1|HYRC|HYRC1|IMD26|XRCC7|p350 / PRKDC / protein kinase, DNA-activated, catalytic polypeptide
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208694_at (Human Genome U133 Plus 2.0 Array)   210543_s_at (Human Genome U133 Plus 2.0 Array)   215757_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 126032350
RefSeq - 13654237
RefSeq - NC_000008.11
RefSeq - NG_023435.1
RefSeq - NP_001075109.1
RefSeq - NP_008835.5
RefSeq - NM_001081640.1
RefSeq - NM_006904.6
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000253729 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0001933 negative regulation of protein phosphorylation ISS
 biological_processGO:0002218 activation of innate immune response IDA
 biological_processGO:0002326 B cell lineage commitment IEA
 biological_processGO:0002328 pro-B cell differentiation IEA
 biological_processGO:0002360 T cell lineage commitment IEA
 biological_processGO:0002638 negative regulation of immunoglobulin production IEA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining TAS
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0006468 protein phosphorylation IMP
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0014823 response to activity IEA
 biological_processGO:0016233 telomere capping IMP
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0032481 positive regulation of type I interferon production TAS
 biological_processGO:0032869 cellular response to insulin stimulus IMP
 biological_processGO:0033077 T cell differentiation in thymus IEA
 biological_processGO:0033152 immunoglobulin V(D)J recombination IEA
 biological_processGO:0033153 T cell receptor V(D)J recombination IEA
 biological_processGO:0035234 ectopic germ cell programmed cell death IEA
 biological_processGO:0042752 regulation of circadian rhythm ISS
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048146 positive regulation of fibroblast proliferation IEA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0048536 spleen development IEA
 biological_processGO:0048538 thymus development IEA
 biological_processGO:0048639 positive regulation of developmental growth IEA
 biological_processGO:0048660 regulation of smooth muscle cell proliferation IMP
 biological_processGO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint IMP
 biological_processGO:0097681 double-strand break repair via alternative nonhomologous end joining TAS
 biological_processGO:2000773 negative regulation of cellular senescence IEA
 biological_processGO:2001229 negative regulation of response to gamma radiation IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region HDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0032993 protein-DNA complex IDA
 cellular_componentGO:0070419 nonhomologous end joining complex IDA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004672 protein kinase activity IMP
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004677 DNA-dependent protein kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0016301 kinase activity IBA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019904 protein domain specific binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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