5595


Homo sapiens (NCBI)

Features
Gene ID: 5595
  
Biological name :
  
Synonyms : ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK / MAPK3 / mitogen-activated protein kinase 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 212046_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001035145.1
RefSeq - NP_001103361.1
RefSeq - NP_002737.2
RefSeq - 158138507
RefSeq - NG_029936.1
RefSeq - 91718897
RefSeq - 91718899
RefSeq - NC_000016.10
RefSeq - XR_243293.1
RefSeq - NM_001040056.2
RefSeq - NM_001109891.1
RefSeq - NM_002746.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000102882 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0002741 positive regulation of cytokine secretion involved in immune response IEA
 biological_processGO:0006361 transcription initiation from RNA polymerase I promoter TAS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006975 DNA damage induced protein phosphorylation IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IBA
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway TAS
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010759 positive regulation of macrophage chemotaxis IEA
 biological_processGO:0014066 regulation of phosphatidylinositol 3-kinase signaling TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016310 phosphorylation IDA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0019369 arachidonic acid metabolic process IEA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030278 regulation of ossification IEA
 biological_processGO:0030509 BMP signaling pathway IMP
 biological_processGO:0030641 regulation of cellular pH IEA
 biological_processGO:0030878 thyroid gland development IEA
 biological_processGO:0031281 positive regulation of cyclase activity IMP
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IMP
 biological_processGO:0032872 regulation of stress-activated MAPK cascade TAS
 biological_processGO:0033129 positive regulation of histone phosphorylation IMP
 biological_processGO:0034198 cellular response to amino acid starvation IDA
 biological_processGO:0034614 cellular response to reactive oxygen species IMP
 biological_processGO:0035066 positive regulation of histone acetylation IMP
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IDA
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0042473 outer ear morphogenesis IEA
 biological_processGO:0043330 response to exogenous dsRNA IEA
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048538 thymus development IEA
 biological_processGO:0051090 regulation of DNA-binding transcription factor activity TAS
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:0051403 stress-activated MAPK cascade IDA
 biological_processGO:0051493 regulation of cytoskeleton organization TAS
 biological_processGO:0051973 positive regulation of telomerase activity IMP
 biological_processGO:0060020 Bergmann glial cell differentiation IEA
 biological_processGO:0060324 face development IEA
 biological_processGO:0060425 lung morphogenesis IEA
 biological_processGO:0060440 trachea formation IEA
 biological_processGO:0061308 cardiac neural crest cell development involved in heart development IEA
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:0070371 ERK1 and ERK2 cascade IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070498 interleukin-1-mediated signaling pathway IMP
 biological_processGO:0070849 response to epidermal growth factor IDA
 biological_processGO:0071260 cellular response to mechanical stimulus IEP
 biological_processGO:0071276 cellular response to cadmium ion IMP
 biological_processGO:0071310 cellular response to organic substance IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0072584 caveolin-mediated endocytosis TAS
 biological_processGO:0090170 regulation of Golgi inheritance TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 biological_processGO:1903351 cellular response to dopamine IMP
 biological_processGO:1904355 positive regulation of telomere capping IMP
 biological_processGO:1904417 positive regulation of xenophagy IEA
 biological_processGO:1905050 positive regulation of metallopeptidase activity IEA
 biological_processGO:2000641 regulation of early endosome to late endosome transport TAS
 biological_processGO:2000657 negative regulation of apolipoprotein binding IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005769 early endosome TAS
 cellular_componentGO:0005770 late endosome TAS
 cellular_componentGO:0005794 Golgi apparatus TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0005901 caveola TAS
 cellular_componentGO:0005925 focal adhesion TAS
 cellular_componentGO:0031143 pseudopodium IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0001784 phosphotyrosine residue binding IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004707 MAP kinase activity TAS
 molecular_functionGO:0004708 MAP kinase kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity TAS
 molecular_functionGO:0019902 phosphatase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0097110 scaffold protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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