5604


Homo sapiens (NCBI)

Features
Gene ID: 5604
  
Biological name :
  
Synonyms : CFC3|MAPKK1|MEK1|MKK1|PRKMK1 / MAP2K1 / mitogen-activated protein kinase kinase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202670_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016877902.1
RefSeq - 1034591303
RefSeq - 1034591305
RefSeq - 5579478
RefSeq - 767984706
RefSeq - NC_000015.10
RefSeq - NG_008305.1
RefSeq - NP_002746.1
RefSeq - XP_011520085.1
RefSeq - XP_016877900.1
RefSeq - XP_016877901.1
RefSeq - 1034591301
RefSeq - NM_002755.3
RefSeq - XM_017022413.1
RefSeq - XM_011521783.3
RefSeq - XM_017022411.2
RefSeq - XM_017022412.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000169032 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0007050 cell cycle arrest IMP
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010629 negative regulation of gene expression IGI
 biological_processGO:0018107 peptidyl-threonine phosphorylation IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0021697 cerebellar cortex formation IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030216 keratinocyte differentiation IEA
 biological_processGO:0030878 thyroid gland development IEA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0032872 regulation of stress-activated MAPK cascade TAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0048538 thymus development IEA
 biological_processGO:0048679 regulation of axon regeneration IEA
 biological_processGO:0048870 cell motility IEA
 biological_processGO:0050772 positive regulation of axonogenesis IEA
 biological_processGO:0060020 Bergmann glial cell differentiation IEA
 biological_processGO:0060324 face development IEA
 biological_processGO:0060440 trachea formation IEA
 biological_processGO:0060502 epithelial cell proliferation involved in lung morphogenesis IEA
 biological_processGO:0060674 placenta blood vessel development IEA
 biological_processGO:0060711 labyrinthine layer development IEA
 biological_processGO:0070371 ERK1 and ERK2 cascade IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IDA
 biological_processGO:0090170 regulation of Golgi inheritance TAS
 biological_processGO:0090398 cellular senescence IMP
 biological_processGO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA IMP
 biological_processGO:2000641 regulation of early endosome to late endosome transport TAS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005769 early endosome TAS
 cellular_componentGO:0005770 late endosome TAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus TAS
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005925 focal adhesion TAS
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004708 MAP kinase kinase activity IDA
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity TAS
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IDA
 molecular_functionGO:0043539 protein serine/threonine kinase activator activity IDA
 molecular_functionGO:0047485 protein N-terminus binding IDA
 molecular_functionGO:0097110 scaffold protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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