5781


Homo sapiens (NCBI)

Features
Gene ID: 5781
  
Biological name :
  
Synonyms : BPTP3|CFC|JMML|METCDS|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2 / protein tyrosine phosphatase, non-receptor type 11 / PTPN11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1552637_at (Human Genome U133 Plus 2.0 Array)   205867_at (Human Genome U133 Plus 2.0 Array)   205868_s_at (Human Genome U133 Plus 2.0 Array)   209895_at (Human Genome U133 Plus 2.0 Array)   209896_s_at (Human Genome U133 Plus 2.0 Array)   212610_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034580860
RefSeq - 1059433492
RefSeq - 18375644
RefSeq - 33356177
RefSeq - 767974975
RefSeq - NC_000012.12
RefSeq - NG_007459.1
RefSeq - NP_001317366.1
RefSeq - NP_002825.3
RefSeq - NP_542168.1
RefSeq - XP_011536915.1
RefSeq - XP_016875211.1
RefSeq - NM_001330437.1
RefSeq - NM_002834.4
RefSeq - NM_080601.2
RefSeq - XM_017019722.1
RefSeq - XM_011538613.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000179295 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IEA
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0006641 triglyceride metabolic process IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway TAS
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0007420 brain development IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway TAS
 biological_processGO:0009755 hormone-mediated signaling pathway IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0021697 cerebellar cortex formation IEA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030220 platelet formation IEA
 biological_processGO:0031295 T cell costimulation TAS
 biological_processGO:0032528 microvillus organization IEA
 biological_processGO:0033277 abortive mitotic cell cycle IEA
 biological_processGO:0033628 regulation of cell adhesion mediated by integrin IMP
 biological_processGO:0033629 negative regulation of cell adhesion mediated by integrin IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0035265 organ growth IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IMP
 biological_processGO:0035855 megakaryocyte development IEA
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0036302 atrioventricular canal development IMP
 biological_processGO:0038127 ERBB signaling pathway IDA
 biological_processGO:0040014 regulation of multicellular organism growth IEA
 biological_processGO:0042445 hormone metabolic process IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043254 regulation of protein complex assembly IDA
 biological_processGO:0045931 positive regulation of mitotic cell cycle IEA
 biological_processGO:0046676 negative regulation of insulin secretion IEA
 biological_processGO:0046825 regulation of protein export from nucleus IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0046887 positive regulation of hormone secretion IEA
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IEA
 biological_processGO:0048011 neurotrophin TRK receptor signaling pathway IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IDA
 biological_processGO:0048609 multicellular organismal reproductive process IEA
 biological_processGO:0048806 genitalia development IMP
 biological_processGO:0048839 inner ear development IMP
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051463 negative regulation of cortisol secretion IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060020 Bergmann glial cell differentiation IEA
 biological_processGO:0060125 negative regulation of growth hormone secretion IEA
 biological_processGO:0060325 face morphogenesis IMP
 biological_processGO:0060338 regulation of type I interferon-mediated signaling pathway TAS
 biological_processGO:0061582 intestinal epithelial cell migration IEA
 biological_processGO:0070102 interleukin-6-mediated signaling pathway TAS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0071260 cellular response to mechanical stimulus IEA
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IMP
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0032991 protein-containing complex IMP
 molecular_functionGO:0001784 phosphotyrosine residue binding IPI
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IDA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity TAS
 molecular_functionGO:0004726 non-membrane spanning protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005070 SH3/SH2 adaptor activity IPI
 molecular_functionGO:0005158 insulin receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA
 molecular_functionGO:0031748 D1 dopamine receptor binding IEA
 molecular_functionGO:0043274 phospholipase binding IEA
 molecular_functionGO:0043560 insulin receptor substrate binding IEA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0050839 cell adhesion molecule binding IEA
 molecular_functionGO:0051428 peptide hormone receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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