581


Homo sapiens (NCBI)

Features
Gene ID: 581
  
Biological name :
  
Synonyms : BAX / BCL2 associated X, apoptosis regulator / BCL2L4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208478_s_at (Human Genome U133 Plus 2.0 Array)   211833_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034608781
RefSeq - 20631958
RefSeq - 20631964
RefSeq - 242117893
RefSeq - 4757838
RefSeq - 612149787
RefSeq - 612149801
RefSeq - 612149804
RefSeq - 612149806
RefSeq - NC_000019.10
RefSeq - NG_012191.1
RefSeq - NP_001278357.1
RefSeq - NP_001278358.1
RefSeq - NP_001278359.1
RefSeq - NP_001278360.1
RefSeq - NP_004315.1
RefSeq - NP_620116.1
RefSeq - NP_620118.1
RefSeq - NP_620119.2
RefSeq - XP_016882566.1
RefSeq - NR_027882.1
RefSeq - XM_017027077.1
RefSeq - NM_001291428.1
RefSeq - NM_001291429.1
RefSeq - NM_001291430.1
RefSeq - NM_001291431.1
RefSeq - NM_004324.3
RefSeq - NM_138761.3
RefSeq - NM_138762.2
RefSeq - NM_138763.3
RefSeq - NM_138764.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000087088 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001541 ovarian follicle development IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0001777 T cell homeostatic proliferation IEA
 biological_processGO:0001782 B cell homeostasis IEA
 biological_processGO:0001783 B cell apoptotic process IDA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001836 release of cytochrome c from mitochondria IDA
 biological_processGO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway TAS
 biological_processGO:0001974 blood vessel remodeling IEA
 biological_processGO:0002262 myeloid cell homeostasis IEA
 biological_processGO:0002352 B cell negative selection IEA
 biological_processGO:0002358 B cell homeostatic proliferation IEA
 biological_processGO:0002904 positive regulation of B cell apoptotic process IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006687 glycosphingolipid metabolic process IEA
 biological_processGO:0006808 regulation of nitrogen utilization IEA
 biological_processGO:0006915 apoptotic process NAS
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0007281 germ cell development IEA
 biological_processGO:0008053 mitochondrial fusion IDA
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IC
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c IDA
 biological_processGO:0008637 apoptotic mitochondrial changes IDA
 biological_processGO:0009566 fertilization IEA
 biological_processGO:0009636 response to toxic substance IDA
 biological_processGO:0009651 response to salt stress IEA
 biological_processGO:0010248 establishment or maintenance of transmembrane electrochemical gradient IDA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0021854 hypothalamus development IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0032461 positive regulation of protein oligomerization IDA
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis TAS
 biological_processGO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration IEA
 biological_processGO:0032976 release of matrix enzymes from mitochondria IDA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0033599 regulation of mammary gland epithelial cell proliferation IEA
 biological_processGO:0034620 cellular response to unfolded protein TAS
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0035234 ectopic germ cell programmed cell death IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0043496 regulation of protein homodimerization activity IDA
 biological_processGO:0043497 regulation of protein heterodimerization activity IPI
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0043525 positive regulation of neuron apoptotic process IDA
 biological_processGO:0043653 mitochondrial fragmentation involved in apoptotic process IDA
 biological_processGO:0045136 development of secondary sexual characteristics IEA
 biological_processGO:0046666 retinal cell programmed cell death IEA
 biological_processGO:0048087 positive regulation of developmental pigmentation IEA
 biological_processGO:0048147 negative regulation of fibroblast proliferation IEA
 biological_processGO:0048515 spermatid differentiation IEA
 biological_processGO:0048597 post-embryonic camera-type eye morphogenesis IEA
 biological_processGO:0048678 response to axon injury IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0051259 protein complex oligomerization IDA
 biological_processGO:0051260 protein homooligomerization IDA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IEA
 biological_processGO:0051402 neuron apoptotic process IEA
 biological_processGO:0051881 regulation of mitochondrial membrane potential IDA
 biological_processGO:0060011 Sertoli cell proliferation IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0060058 positive regulation of apoptotic process involved in mammary gland involution IEA
 biological_processGO:0060068 vagina development IEA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress TAS
 biological_processGO:0070242 thymocyte apoptotic process IEA
 biological_processGO:0070584 mitochondrion morphogenesis IEA
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IEA
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria IMP
 biological_processGO:0097190 apoptotic signaling pathway IDA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IDA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IBA
 biological_processGO:0097193 intrinsic apoptotic signaling pathway IDA
 biological_processGO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IEA
 biological_processGO:1900103 positive regulation of endoplasmic reticulum unfolded protein response IMP
 biological_processGO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway TAS
 biological_processGO:1902262 apoptotic process involved in blood vessel morphogenesis IEA
 biological_processGO:1902263 apoptotic process involved in embryonic digit morphogenesis IEA
 biological_processGO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death IEA
 biological_processGO:1902512 positive regulation of apoptotic DNA fragmentation IMP
 biological_processGO:1903896 positive regulation of IRE1-mediated unfolded protein response TAS
 biological_processGO:1990117 B cell receptor apoptotic signaling pathway IDA
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IEA
 biological_processGO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005634 nucleus IMP
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005757 mitochondrial permeability transition pore complex IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0046930 pore complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071944 cell periphery IDA
 cellular_componentGO:0097136 Bcl-2 family protein complex IDA
 cellular_componentGO:0097144 BAX complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IDA
 molecular_functionGO:0015267 channel activity IDA
 molecular_functionGO:0030544 Hsp70 protein binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0051087 chaperone binding IEA
 molecular_functionGO:0051434 BH3 domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr