5894


Homo sapiens (NCBI)

Features
Gene ID: 5894
  
Biological name :
  
Synonyms : CMD1NN|CRAF|NS5|Raf-1|c-Raf / RAF1 / Raf-1 proto-oncogene, serine/threonine kinase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1557675_at (Human Genome U133 Plus 2.0 Array)   201244_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001341620.1
RefSeq - NP_001341621.1
RefSeq - NP_001341622.1
RefSeq - NP_001341623.1
RefSeq - NP_001341624.1
RefSeq - NP_002871.1
RefSeq - 767923931
RefSeq - NC_000003.12
RefSeq - NG_007467.1
RefSeq - 1233267483
RefSeq - 1233267522
RefSeq - XP_011532276.1
RefSeq - XP_016862455.1
RefSeq - 1034634870
RefSeq - 1237937656
RefSeq - 1237937772
RefSeq - 1237938104
RefSeq - 1237938372
RefSeq - 1241781456
RefSeq - 4506401
RefSeq - NP_001341618.1
RefSeq - NP_001341619.1
RefSeq - XR_001740227.1
RefSeq - NM_001354689.1
RefSeq - NM_001354690.1
RefSeq - NM_001354691.1
RefSeq - NM_001354692.1
RefSeq - NM_001354693.1
RefSeq - NM_001354694.1
RefSeq - NM_001354695.1
RefSeq - NM_002880.3
RefSeq - NR_148940.1
RefSeq - NR_148941.1
RefSeq - NR_148942.1
RefSeq - XM_011533974.3
RefSeq - XM_017006966.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000132155 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000186 activation of MAPKK activity IDA
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007190 activation of adenylate cyclase activity IDA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030878 thyroid gland development IEA
 biological_processGO:0031333 negative regulation of protein complex assembly IDA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction TAS
 biological_processGO:0035773 insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0035994 response to muscle stretch IEA
 biological_processGO:0042060 wound healing TAS
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process TAS
 biological_processGO:0045104 intermediate filament cytoskeleton organization IEA
 biological_processGO:0045595 regulation of cell differentiation TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048011 neurotrophin TRK receptor signaling pathway IEA
 biological_processGO:0048538 thymus development IEA
 biological_processGO:0060324 face development IEA
 biological_processGO:0071550 death-inducing signaling complex assembly IEA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:2000145 regulation of cell motility TAS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IPI
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0031143 pseudopodium IEA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008179 adenylate cyclase binding IEA
 molecular_functionGO:0010856 adenylate cyclase activator activity IEA
 molecular_functionGO:0016301 kinase activity TAS
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0031267 small GTPase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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