5914


Homo sapiens (NCBI)

Features
Gene ID: 5914
  
Biological name :
  
Synonyms : NR1B1|RAR / RARA / retinoic acid receptor alpha
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1565358_at (Human Genome U133 Plus 2.0 Array)   203749_s_at (Human Genome U133 Plus 2.0 Array)   203750_s_at (Human Genome U133 Plus 2.0 Array)   211605_s_at (Human Genome U133 Plus 2.0 Array)   216300_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034600712
RefSeq - 223718064
RefSeq - 223718070
RefSeq - 4506419
RefSeq - 530412616
RefSeq - 530412618
RefSeq - 530412620
RefSeq - 67459914
RefSeq - 767995505
RefSeq - 767995507
RefSeq - NC_000017.11
RefSeq - NG_027701.1
RefSeq - NP_000955.1
RefSeq - NP_001019980.1
RefSeq - NP_001138773.1
RefSeq - NP_001138774.1
RefSeq - XP_005257609.1
RefSeq - XP_005257610.1
RefSeq - XP_005257611.1
RefSeq - XP_011523397.1
RefSeq - XP_011523398.1
RefSeq - XP_016880409.1
RefSeq - XM_005257553.1
RefSeq - NM_000964.3
RefSeq - NM_001024809.3
RefSeq - NM_001033603.1
RefSeq - NM_001145301.2
RefSeq - NM_001145302.2
RefSeq - XM_005257554.1
RefSeq - XM_011525095.1
RefSeq - XM_011525096.1
RefSeq - XM_017024920.2
RefSeq - XM_005257552.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000131759 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001657 ureteric bud development IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0002068 glandular epithelial cell development IEA
 biological_processGO:0003148 outflow tract septum morphogenesis IEA
 biological_processGO:0003417 growth plate cartilage development IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006468 protein phosphorylation IMP
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007281 germ cell development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007420 brain development IBA
 biological_processGO:0007507 heart development IBA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009755 hormone-mediated signaling pathway IBA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030850 prostate gland development IEA
 biological_processGO:0030853 negative regulation of granulocyte differentiation IDA
 biological_processGO:0030855 epithelial cell differentiation IBA
 biological_processGO:0031076 embryonic camera-type eye development IEA
 biological_processGO:0031641 regulation of myelination IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032526 response to retinoic acid IMP
 biological_processGO:0032689 negative regulation of interferon-gamma production IDA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IDA
 biological_processGO:0032736 positive regulation of interleukin-13 production IDA
 biological_processGO:0032753 positive regulation of interleukin-4 production IDA
 biological_processGO:0032754 positive regulation of interleukin-5 production IDA
 biological_processGO:0033189 response to vitamin A IEA
 biological_processGO:0033993 response to lipid IBA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043277 apoptotic cell clearance IMP
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045630 positive regulation of T-helper 2 cell differentiation IDA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0045787 positive regulation of cell cycle IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0045947 negative regulation of translational initiation IEA
 biological_processGO:0048167 regulation of synaptic plasticity IEA
 biological_processGO:0048384 retinoic acid receptor signaling pathway IMP
 biological_processGO:0048568 embryonic organ development IBA
 biological_processGO:0048732 gland development IBA
 biological_processGO:0051099 positive regulation of binding IMP
 biological_processGO:0055012 ventricular cardiac muscle cell differentiation IEA
 biological_processGO:0060010 Sertoli cell fate commitment IEA
 biological_processGO:0060173 limb development IEA
 biological_processGO:0060324 face development IEA
 biological_processGO:0060349 bone morphogenesis IBA
 biological_processGO:0060429 epithelium development IBA
 biological_processGO:0060534 trachea cartilage development IEA
 biological_processGO:0060591 chondroblast differentiation IEA
 biological_processGO:0061037 negative regulation of cartilage development IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071300 cellular response to retinoic acid IDA
 biological_processGO:0071391 cellular response to estrogen stimulus IDA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0009986 cell surface IC
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IBA
 molecular_functionGO:0000900 translation repressor activity, mRNA regulatory element binding IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0001972 retinoic acid binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0003708 retinoic acid receptor activity IDA
 molecular_functionGO:0003713 transcription coactivator activity IMP
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0004879 nuclear receptor activity IBA
 molecular_functionGO:0005102 signaling receptor binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IBA
 molecular_functionGO:0031490 chromatin DNA binding IDA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0043422 protein kinase B binding IPI
 molecular_functionGO:0044323 retinoic acid-responsive element binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0048027 mRNA 5"-UTR binding IEA
 molecular_functionGO:0051018 protein kinase A binding IDA
 molecular_functionGO:0051393 alpha-actinin binding IPI
 molecular_functionGO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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