596


Homo sapiens (NCBI)

Features
Gene ID: 596
  
Biological name :
  
Synonyms : BCL2 / BCL2, apoptosis regulator / Bcl-2|PPP1R50
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203684_s_at (Human Genome U133 Plus 2.0 Array)   203685_at (Human Genome U133 Plus 2.0 Array)   207004_at (Human Genome U133 Plus 2.0 Array)   207005_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767999127
RefSeq - NC_000018.10
RefSeq - XP_011524437.1
RefSeq - XP_016881406.1
RefSeq - 1034604526
RefSeq - NG_009361.1
RefSeq - 72198189
RefSeq - 72198346
RefSeq - NP_000624.2
RefSeq - NP_000648.2
RefSeq - XR_935248.3
RefSeq - NM_000633.2
RefSeq - NM_000657.2
RefSeq - XM_011526135.3
RefSeq - XM_017025917.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000171791 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0001503 ossification IEA
 biological_processGO:0001541 ovarian follicle development IEA
 biological_processGO:0001656 metanephros development IEA
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0001662 behavioral fear response IEA
 biological_processGO:0001782 B cell homeostasis IEA
 biological_processGO:0001836 release of cytochrome c from mitochondria NAS
 biological_processGO:0001952 regulation of cell-matrix adhesion IEA
 biological_processGO:0002320 lymphoid progenitor cell differentiation IEA
 biological_processGO:0002326 B cell lineage commitment IEA
 biological_processGO:0002931 response to ischemia IEA
 biological_processGO:0003014 renal system process IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0006582 melanin metabolic process IEA
 biological_processGO:0006808 regulation of nitrogen utilization IEA
 biological_processGO:0006915 apoptotic process IDA
 biological_processGO:0006959 humoral immune response TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0007565 female pregnancy NAS
 biological_processGO:0007569 cell aging IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IDA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress IEA
 biological_processGO:0009314 response to radiation NAS
 biological_processGO:0009636 response to toxic substance IDA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010039 response to iron ion IDA
 biological_processGO:0010224 response to UV-B IEA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010507 negative regulation of autophagy TAS
 biological_processGO:0010523 negative regulation of calcium ion transport into cytosol IEA
 biological_processGO:0010559 regulation of glycoprotein biosynthetic process IEA
 biological_processGO:0014031 mesenchymal cell development IEA
 biological_processGO:0014042 positive regulation of neuron maturation IEA
 biological_processGO:0014911 positive regulation of smooth muscle cell migration IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0021747 cochlear nucleus development IEA
 biological_processGO:0022612 gland morphogenesis IEA
 biological_processGO:0022898 regulation of transmembrane transporter activity IDA
 biological_processGO:0030279 negative regulation of ossification IEA
 biological_processGO:0030307 positive regulation of cell growth IDA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0030318 melanocyte differentiation IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0030890 positive regulation of B cell proliferation IMP
 biological_processGO:0031069 hair follicle morphogenesis IEA
 biological_processGO:0031103 axon regeneration IEA
 biological_processGO:0031647 regulation of protein stability IEA
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis TAS
 biological_processGO:0032835 glomerulus development IEA
 biological_processGO:0032848 negative regulation of cellular pH reduction IDA
 biological_processGO:0033033 negative regulation of myeloid cell apoptotic process IEA
 biological_processGO:0033077 T cell differentiation in thymus IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0033689 negative regulation of osteoblast proliferation IEA
 biological_processGO:0034097 response to cytokine IDA
 biological_processGO:0035094 response to nicotine IDA
 biological_processGO:0035265 organ growth IEA
 biological_processGO:0040018 positive regulation of multicellular organism growth IEA
 biological_processGO:0042100 B cell proliferation IDA
 biological_processGO:0042149 cellular response to glucose starvation IEA
 biological_processGO:0042493 response to drug IMP
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0043029 T cell homeostasis IEA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0043375 CD8-positive, alpha-beta T cell lineage commitment IEA
 biological_processGO:0043496 regulation of protein homodimerization activity IDA
 biological_processGO:0043497 regulation of protein heterodimerization activity IDA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IDA
 biological_processGO:0043583 ear development IEA
 biological_processGO:0045069 regulation of viral genome replication IEA
 biological_processGO:0045636 positive regulation of melanocyte differentiation IEA
 biological_processGO:0046671 negative regulation of retinal cell programmed cell death IEA
 biological_processGO:0046902 regulation of mitochondrial membrane permeability ISS
 biological_processGO:0048041 focal adhesion assembly IEA
 biological_processGO:0048536 spleen development IEA
 biological_processGO:0048538 thymus development IEA
 biological_processGO:0048546 digestive tract morphogenesis IEA
 biological_processGO:0048599 oocyte development IEA
 biological_processGO:0048743 positive regulation of skeletal muscle fiber development IEA
 biological_processGO:0048753 pigment granule organization IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0050853 B cell receptor signaling pathway IMP
 biological_processGO:0051384 response to glucocorticoid IEA
 biological_processGO:0051402 neuron apoptotic process TAS
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0051881 regulation of mitochondrial membrane potential ISS
 biological_processGO:0051902 negative regulation of mitochondrial depolarization TAS
 biological_processGO:0051924 regulation of calcium ion transport IDA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IDA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway TAS
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IEA
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process IEA
 biological_processGO:2000811 negative regulation of anoikis IMP
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IMP
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IGI
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IDA
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0046930 pore complex IDA
 molecular_functionGO:0002020 protease binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0015267 channel activity IDA
 molecular_functionGO:0016248 channel inhibitor activity IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0051434 BH3 domain binding IPI
 molecular_functionGO:0051721 protein phosphatase 2A binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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