5979


Homo sapiens (NCBI)

Features
Gene ID: 5979
  
Biological name :
  
Synonyms : CDHF12|CDHR16|HSCR1|MEN2A|MEN2B|MTC1|PTC|RET-ELE1 / RET / ret proto-oncogene
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205879_x_at (Human Genome U133 Plus 2.0 Array)   211421_s_at (Human Genome U133 Plus 2.0 Array)   215771_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 10862701
RefSeq - 10862703
RefSeq - 1241781396
RefSeq - NC_000010.11
RefSeq - NG_007489.1
RefSeq - NP_001342145.1
RefSeq - NP_065681.1
RefSeq - NP_066124.1
RefSeq - NM_020630.5
RefSeq - NM_020975.5
RefSeq - NM_000323.2
RefSeq - NM_001355216.1
RefSeq - NM_020629.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000165731 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000187 activation of MAPK activity IMP
 biological_processGO:0001657 ureteric bud development IEA
 biological_processGO:0001755 neural crest cell migration IEA
 biological_processGO:0001838 embryonic epithelial tube formation IEA
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007158 neuron cell-cell adhesion IMP
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0007497 posterior midgut development TAS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010976 positive regulation of neuron projection development IMP
 biological_processGO:0014042 positive regulation of neuron maturation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030155 regulation of cell adhesion IDA
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein IEA
 biological_processGO:0033619 membrane protein proteolysis IDA
 biological_processGO:0033630 positive regulation of cell adhesion mediated by integrin IDA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035799 ureter maturation IEA
 biological_processGO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway IDA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042551 neuron maturation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0045793 positive regulation of cell size IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0048265 response to pain ISS
 biological_processGO:0048484 enteric nervous system development IEA
 biological_processGO:0050770 regulation of axonogenesis IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IMP
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0060384 innervation IEA
 biological_processGO:0061146 Peyer"s patch morphogenesis ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071300 cellular response to retinoic acid IMP
 biological_processGO:0072300 positive regulation of metanephric glomerulus development ISS
 biological_processGO:0097021 lymphocyte migration into lymphoid organs ISS
 biological_processGO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0010008 endosome membrane IDA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0098797 plasma membrane protein complex IDA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038023 signaling receptor activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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