6464


Homo sapiens (NCBI)

Features
Gene ID: 6464
  
Biological name :
  
Synonyms : SHC1 / SHC adaptor protein 1 / SHC|SHCA
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 201469_s_at (Human Genome U133 Plus 2.0 Array)   214853_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767910197
RefSeq - 1034561053
RefSeq - 1034561056
RefSeq - 1370454200
RefSeq - 1370454202
RefSeq - 194239662
RefSeq - 194239664
RefSeq - 194239668
RefSeq - 322302755
RefSeq - 32261324
RefSeq - 530365298
RefSeq - 530365302
RefSeq - 1034561051
RefSeq - 767910199
RefSeq - 767910201
RefSeq - 767910208
RefSeq - 767910210
RefSeq - NC_000001.11
RefSeq - NG_029028.1
RefSeq - NP_001123512.1
RefSeq - NP_001123513.1
RefSeq - NP_001189788.1
RefSeq - NP_003020.2
RefSeq - NP_892113.4
RefSeq - XP_005245506.1
RefSeq - XP_005245508.1
RefSeq - XP_011508194.1
RefSeq - XP_011508195.1
RefSeq - XP_011508196.1
RefSeq - XP_011508199.1
RefSeq - XP_011508200.1
RefSeq - XP_016857570.1
RefSeq - XP_016857571.1
RefSeq - XP_016857572.1
RefSeq - XP_024304851.1
RefSeq - XP_024304852.1
RefSeq - NM_001130040.1
RefSeq - NM_001130041.1
RefSeq - NM_001202859.1
RefSeq - NM_003029.4
RefSeq - NM_183001.4
RefSeq - XM_017002081.2
RefSeq - XM_017002082.2
RefSeq - XM_017002083.1
RefSeq - XM_024449083.1
RefSeq - XM_024449084.1
RefSeq - XM_005245449.5
RefSeq - XM_005245451.4
RefSeq - XM_011509892.3
RefSeq - XM_011509893.3
RefSeq - XM_011509894.3
RefSeq - XM_011509897.1
RefSeq - XM_011509898.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000160691 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000187 activation of MAPK activity IMP
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway TAS
 biological_processGO:0007176 regulation of epidermal growth factor-activated receptor activity TAS
 biological_processGO:0007265 Ras protein signal transduction TAS
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008284 positive regulation of cell proliferation NAS
 biological_processGO:0008286 insulin receptor signaling pathway TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0035723 interleukin-15-mediated signaling pathway TAS
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0038110 interleukin-2-mediated signaling pathway TAS
 biological_processGO:0038128 ERBB2 signaling pathway TAS
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0042742 defense response to bacterium IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0071363 cellular response to growth factor stimulus IDA
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0070435 Shc-EGFR complex ISS
 molecular_functionGO:0001784 phosphotyrosine residue binding IPI
 molecular_functionGO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity TAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005154 epidermal growth factor receptor binding ISS
 molecular_functionGO:0005158 insulin receptor binding IPI
 molecular_functionGO:0005159 insulin-like growth factor receptor binding IPI
 molecular_functionGO:0005168 neurotrophin TRKA receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding TAS
 molecular_functionGO:0019901 protein kinase binding IBA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IBA
 molecular_functionGO:0046875 ephrin receptor binding IPI
 molecular_functionGO:0048408 epidermal growth factor binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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