64750


Homo sapiens (NCBI)

Features
Gene ID: 64750
  
Biological name :
  
Synonyms : SMAD specific E3 ubiquitin protein ligase 2 / SMURF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205596_s_at (Human Genome U133 Plus 2.0 Array)   227489_at (Human Genome U133 Plus 2.0 Array)   232020_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 530412684
RefSeq - XP_005257642.1
RefSeq - NC_000017.11
RefSeq - 12232397
RefSeq - NP_073576.1
RefSeq - NM_022739.3
RefSeq - XM_005257585.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000108854 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0016567 protein ubiquitination IBA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0017015 regulation of transforming growth factor beta receptor signaling pathway NAS
 biological_processGO:0030509 BMP signaling pathway TAS
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0030514 negative regulation of BMP signaling pathway IBA
 biological_processGO:0030579 ubiquitin-dependent SMAD protein catabolic process IDA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0045732 positive regulation of protein catabolic process IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated NAS
 biological_processGO:0060071 Wnt signaling pathway, planar cell polarity pathway TAS
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway TAS
 biological_processGO:1901165 positive regulation of trophoblast cell migration IDA
 cellular_componentGO:0000151 ubiquitin ligase complex IDA
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046332 SMAD binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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