659


Homo sapiens (NCBI)

Features
Gene ID: 659
  
Biological name :
  
Synonyms : BMPR2 / BMPR-II|BMPR3|BMR2|BRK-3|POVD1|PPH1|T-ALK / bone morphogenetic protein receptor type 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209920_at (Human Genome U133 Plus 2.0 Array)   210214_s_at (Human Genome U133 Plus 2.0 Array)   225144_at (Human Genome U133 Plus 2.0 Array)   231873_at (Human Genome U133 Plus 2.0 Array)   238516_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 15451916
RefSeq - 767919393
RefSeq - NC_000002.12
RefSeq - NG_009363.1
RefSeq - NP_001195.2
RefSeq - XP_011509989.1
RefSeq - XM_011511687.1
RefSeq - NM_001204.6
RefSeq - NM_033346.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000204217 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IBA
 biological_processGO:0001707 mesoderm formation ISS
 biological_processGO:0001893 maternal placenta development IEA
 biological_processGO:0001935 endothelial cell proliferation IMP
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IMP
 biological_processGO:0001944 vasculature development IBA
 biological_processGO:0001946 lymphangiogenesis ISS
 biological_processGO:0001974 blood vessel remodeling ISS
 biological_processGO:0002063 chondrocyte development IMP
 biological_processGO:0003085 negative regulation of systemic arterial blood pressure IMP
 biological_processGO:0003148 outflow tract septum morphogenesis ISS
 biological_processGO:0003151 outflow tract morphogenesis ISS
 biological_processGO:0003181 atrioventricular valve morphogenesis ISS
 biological_processGO:0003183 mitral valve morphogenesis ISS
 biological_processGO:0003186 tricuspid valve morphogenesis ISS
 biological_processGO:0003197 endocardial cushion development ISS
 biological_processGO:0003252 negative regulation of cell proliferation involved in heart valve morphogenesis ISS
 biological_processGO:0006366 transcription by RNA polymerase II IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway IDA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IBA
 biological_processGO:0007389 pattern specification process IBA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0009267 cellular response to starvation IEP
 biological_processGO:0009952 anterior/posterior pattern specification ISS
 biological_processGO:0010595 positive regulation of endothelial cell migration IMP
 biological_processGO:0010634 positive regulation of epithelial cell migration IDA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IMP
 biological_processGO:0014916 regulation of lung blood pressure ISS
 biological_processGO:0030166 proteoglycan biosynthetic process ISS
 biological_processGO:0030308 negative regulation of cell growth IDA
 biological_processGO:0030501 positive regulation of bone mineralization IMP
 biological_processGO:0030509 BMP signaling pathway TAS
 biological_processGO:0030513 positive regulation of BMP signaling pathway IMP
 biological_processGO:0032924 activin receptor signaling pathway IEA
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0045669 positive regulation of osteoblast differentiation IMP
 biological_processGO:0045778 positive regulation of ossification ISS
 biological_processGO:0045906 negative regulation of vasoconstriction ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway ISS
 biological_processGO:0048286 lung alveolus development ISS
 biological_processGO:0048738 cardiac muscle tissue development ISS
 biological_processGO:0048842 positive regulation of axon extension involved in axon guidance IEA
 biological_processGO:0060173 limb development IEA
 biological_processGO:0060350 endochondral bone morphogenesis ISS
 biological_processGO:0060412 ventricular septum morphogenesis ISS
 biological_processGO:0060413 atrial septum morphogenesis ISS
 biological_processGO:0060836 lymphatic endothelial cell differentiation ISS
 biological_processGO:0060840 artery development ISS
 biological_processGO:0060841 venous blood vessel development ISS
 biological_processGO:0061036 positive regulation of cartilage development ISS
 biological_processGO:0061298 retina vasculature development in camera-type eye ISS
 biological_processGO:0061626 pharyngeal arch artery morphogenesis ISS
 biological_processGO:0071773 cellular response to BMP stimulus IMP
 biological_processGO:0072577 endothelial cell apoptotic process IMP
 biological_processGO:1902731 negative regulation of chondrocyte proliferation IMP
 biological_processGO:1905314 semi-lunar valve development ISS
 biological_processGO:2000279 negative regulation of DNA biosynthetic process IMP
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005901 caveola IMP
 cellular_componentGO:0005913 cell-cell adherens junction IDA
 cellular_componentGO:0009925 basal plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0044214 spanning component of plasma membrane TAS
 molecular_functionGO:0005024 transforming growth factor beta-activated receptor activity IBA
 molecular_functionGO:0005026 transforming growth factor beta receptor activity, type II IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016362 activin receptor activity, type II TAS
 molecular_functionGO:0019838 growth factor binding IEA
 molecular_functionGO:0036122 BMP binding IPI
 molecular_functionGO:0046332 SMAD binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0098821 BMP receptor activity ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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