6653


Homo sapiens (NCBI)

Features
Gene ID: 6653
  
Biological name :
  
Synonyms : C11orf32|LR11|LRP9|SORLA|SorLA-1|gp250 / SORL1 / sortilin related receptor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203509_at (Human Genome U133 Plus 2.0 Array)   212560_at (Human Genome U133 Plus 2.0 Array)   230707_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034575033
RefSeq - 1034575035
RefSeq - 1034575037
RefSeq - 1034575040
RefSeq - 4507157
RefSeq - 767970511
RefSeq - 767970515
RefSeq - 767970519
RefSeq - NC_000011.10
RefSeq - NG_023313.1
RefSeq - NP_003096.1
RefSeq - XP_011541265.1
RefSeq - XP_011541267.1
RefSeq - XP_011541269.1
RefSeq - XP_016873658.1
RefSeq - XP_016873659.1
RefSeq - XP_016873660.1
RefSeq - XP_016873661.1
RefSeq - NM_003105.5
RefSeq - XM_017018172.2
RefSeq - XM_011542963.3
RefSeq - XM_011542965.3
RefSeq - XM_011542967.3
RefSeq - XM_017018169.2
RefSeq - XM_017018170.2
RefSeq - XM_017018171.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000137642 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting IMP
 biological_processGO:0006622 protein targeting to lysosome IDA
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0006892 post-Golgi vesicle-mediated transport IDA
 biological_processGO:0006898 receptor-mediated endocytosis TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0014910 regulation of smooth muscle cell migration IDA
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0032460 negative regulation of protein oligomerization IMP
 biological_processGO:0034067 protein localization to Golgi apparatus IDA
 biological_processGO:0043407 negative regulation of MAP kinase activity ISS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0045053 protein retention in Golgi apparatus IDA
 biological_processGO:0045732 positive regulation of protein catabolic process IDA
 biological_processGO:0050768 negative regulation of neurogenesis ISS
 biological_processGO:0051604 protein maturation IDA
 biological_processGO:0070863 positive regulation of protein exit from endoplasmic reticulum IMP
 biological_processGO:1901215 negative regulation of neuron death ISS
 biological_processGO:1902430 negative regulation of amyloid-beta formation IMP
 biological_processGO:1902771 positive regulation of choline O-acetyltransferase activity ISS
 biological_processGO:1902948 negative regulation of tau-protein kinase activity ISS
 biological_processGO:1902953 positive regulation of ER to Golgi vesicle-mediated transport IMP
 biological_processGO:1902955 positive regulation of early endosome to recycling endosome transport IMP
 biological_processGO:1902960 negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process IMP
 biological_processGO:1902963 negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process IMP
 biological_processGO:1902966 positive regulation of protein localization to early endosome IMP
 biological_processGO:1902997 negative regulation of neurofibrillary tangle assembly ISS
 biological_processGO:2001137 positive regulation of endocytic recycling IMP
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005641 nuclear envelope lumen IDA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome IMP
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0031985 Golgi cisterna IDA
 cellular_componentGO:0034362 low-density lipoprotein particle IEA
 cellular_componentGO:0055037 recycling endosome IMP
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001540 amyloid-beta binding IPI
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005041 low-density lipoprotein particle receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030169 low-density lipoprotein particle binding IPI
 molecular_functionGO:0030306 ADP-ribosylation factor binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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