672


Homo sapiens (NCBI)

Features
Gene ID: 672
  
Biological name :
  
Synonyms : BRCA1 / BRCA1, DNA repair associated / BRCAI|BRCC1|BROVCA1|FANCS|IRIS|PNCA4|PPP1R53|PSCP|RNF53
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204531_s_at (Human Genome U133 Plus 2.0 Array)   211851_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 237681121
RefSeq - 237681123
RefSeq - 237681125
RefSeq - 6552299
RefSeq - NC_000017.11
RefSeq - NG_005905.2
RefSeq - NP_009225.1
RefSeq - NP_009228.2
RefSeq - NP_009229.2
RefSeq - NP_009230.2
RefSeq - NP_009231.2
RefSeq - 237681119
RefSeq - NM_007306.2
RefSeq - NR_027676.1
RefSeq - NM_007294.3
RefSeq - NM_007295.2
RefSeq - NM_007296.2
RefSeq - NM_007297.3
RefSeq - NM_007298.3
RefSeq - NM_007299.3
RefSeq - NM_007300.3
RefSeq - NM_007301.2
RefSeq - NM_007302.2
RefSeq - NM_007303.2
RefSeq - NM_007305.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000012048 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IDA
 biological_processGO:0000729 DNA double-strand break processing TAS
 biological_processGO:0006260 DNA replication TAS
 biological_processGO:0006301 postreplication repair IDA
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining TAS
 biological_processGO:0006349 regulation of gene expression by genetic imprinting IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006359 regulation of transcription by RNA polymerase III TAS
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus TAS
 biological_processGO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator TAS
 biological_processGO:0007059 chromosome segregation IMP
 biological_processGO:0007098 centrosome cycle IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IDA
 biological_processGO:0009048 dosage compensation by inactivation of X chromosome IBA
 biological_processGO:0010212 response to ionizing radiation IMP
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production IMP
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0030521 androgen receptor signaling pathway NAS
 biological_processGO:0031398 positive regulation of protein ubiquitination IDA
 biological_processGO:0033147 negative regulation of intracellular estrogen receptor signaling pathway IMP
 biological_processGO:0035066 positive regulation of histone acetylation IDA
 biological_processGO:0035067 negative regulation of histone acetylation IBA
 biological_processGO:0042127 regulation of cell proliferation TAS
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043009 chordate embryonic development IBA
 biological_processGO:0043627 response to estrogen IDA
 biological_processGO:0044030 regulation of DNA methylation IEA
 biological_processGO:0044818 mitotic G2/M transition checkpoint IEA
 biological_processGO:0045717 negative regulation of fatty acid biosynthetic process IMP
 biological_processGO:0045739 positive regulation of DNA repair IMP
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0046600 negative regulation of centriole replication NAS
 biological_processGO:0051571 positive regulation of histone H3-K4 methylation IDA
 biological_processGO:0051572 negative regulation of histone H3-K4 methylation IEA
 biological_processGO:0051573 negative regulation of histone H3-K9 methylation IDA
 biological_processGO:0051574 positive regulation of histone H3-K9 methylation IEA
 biological_processGO:0051865 protein autoubiquitination IDA
 biological_processGO:0070317 negative regulation of G0 to G1 transition TAS
 biological_processGO:0070512 positive regulation of histone H4-K20 methylation IDA
 biological_processGO:0071158 positive regulation of cell cycle arrest IDA
 biological_processGO:0071356 cellular response to tumor necrosis factor IMP
 biological_processGO:0071681 cellular response to indole-3-methanol IDA
 biological_processGO:0072425 signal transduction involved in G2 DNA damage checkpoint IMP
 biological_processGO:0085020 protein K6-linked ubiquitination IDA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IMP
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process IMP
 biological_processGO:2000617 positive regulation of histone H3-K9 acetylation IDA
 biological_processGO:2000620 positive regulation of histone H4-K16 acetylation IDA
 cellular_componentGO:0000151 ubiquitin ligase complex NAS
 cellular_componentGO:0000800 lateral element IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome ISS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0008274 gamma-tubulin ring complex NAS
 cellular_componentGO:0031436 BRCA1-BARD1 complex IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0070531 BRCA1-A complex IDA
 cellular_componentGO:1990904 ribonucleoprotein complex IDA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003713 transcription coactivator activity NAS
 molecular_functionGO:0003723 RNA binding IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0015631 tubulin binding NAS
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0050681 androgen receptor binding NAS
 molecular_functionGO:0070063 RNA polymerase binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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