67451


Mus musculus (NCBI)
junctioncellcardiacregulationassemblycell-cellmusclebindingactionpotentialdesmosomeadherensintermediatefilamentventricularproteininvolvedheartmaintenancebundleplasmamembraneconductionadhesionorganizationdevelopmentproliferationsignaltransductiongap

Features
Gene ID: 67451
  
Biological name :
  
Synonyms : 1200008D14Rik|1200012P04Rik|AA516617|Pkp2l / Pkp2 / plakophilin 2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1420259_at (Mouse Genome 430 2.0 Array)   1429183_at (Mouse Genome 430 2.0 Array)   1449799_s_at (Mouse Genome 430 2.0 Array)   1460511_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 21312960
RefSeq - NC_000082.6
RefSeq - NP_080439.1
RefSeq - NM_026163.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000041957 to get all the annotations available for this gene.


Gene Ontology (GO)
cellular component organizationcellular component biogenesisanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentintermediate filament-based processcellular developmental processregulation of biological qualitymacromolecule localizationcellular localizationsystem processactin filament-based processmulticellular organismal signalingcell adhesioncellular component organizationcellular component biogenesisanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentintermediate filament-based processcellular developmental processregulation of biological qualitymacromolecule localizationcellular localizationsystem processactin filament-based processmulticellular organismal signalingcell adhesioncellular component organizationcellular component biogenesisanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentintermediate filament-based processcellular developmental processregulation of biological qualitymacromolecule localizationcellular localizationsystem processactin filament-based processmulticellular organismal signalingcell adhesioncellular component organizationcellular component biogenesisanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentintermediate filament-based processcellular developmental processregulation of biological qualitymacromolecule localizationcellular localizationsystem processactin filament-based processmulticellular organismal signalingcell adhesioncellular component organizationcellular component biogenesisanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentintermediate filament-based processcellular developmental processregulation of biological qualitymacromolecule localizationcellular localizationsystem processactin filament-based processmulticellular organismal signalingcell adhesioncellular component organizationcellular component biogenesisanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentintermediate filament-based processcellular developmental processregulation of biological qualitymacromolecule localizationcellular localizationsystem processactin filament-based processmulticellular organismal signalingcell adhesioncellular component organizationcellular component biogenesisanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentintermediate filament-based processcellular developmental processregulation of biological qualitymacromolecule localizationcellular localizationsystem processactin filament-based processmulticellular organismal signalingcell adhesioncellular component organizationcellular component biogenesisanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentintermediate filament-based processcellular developmental processregulation of biological qualitymacromolecule localizationcellular localizationsystem processactin filament-based processmulticellular organismal signalingcell adhesioncellular component organizationcellular component biogenesisanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentintermediate filament-based processcellular developmental processregulation of biological qualitymacromolecule localizationcellular localizationsystem processactin filament-based processmulticellular organismal signalingcell adhesioncellular component organizationcellular component biogenesisanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentintermediate filament-based processcellular developmental processregulation of biological qualitymacromolecule localizationcellular localizationsystem processactin filament-based processmulticellular organismal signalingcell adhesioncellularcellular component organizationcellularcellular component biogenesisanatomicanatomical structure developmentcell comcell communicationcellularcellular response to stimuluslocalizalocalization of cellmovementmovement of cell or subcellular componentintermedintermediate filament-based processcellularcellular developmental processregulatiregulation of biological qualitymacromolmacromolecule localizationcellularcellular localizationsystem psystem processactin fiactin filament-based processmulticelmulticellular organismal signalingcell adhcell adhesion
protein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein bindingprotein-containing complex bindingprotein-containing complex binding
cellorganellemembrane-enclosed lumensupramolecular complexmembranecell junctioncellorganellemembrane-enclosed lumensupramolecular complexmembranecell junctioncellorganellemembrane-enclosed lumensupramolecular complexmembranecell junctioncellorganellemembrane-enclosed lumensupramolecular complexmembranecell junctioncellorganellemembrane-enclosed lumensupramolecular complexmembranecell junctioncellorganellemembrane-enclosed lumensupramolecular complexmembranecell junctioncellorganellemembrane-enclosed lumensupramolecular complexmembranecell junctioncellorganellemembrane-enclosed lumensupramolecular complexmembranecell junctioncellorganellemembrane-enclosed lumensupramolecular complexmembranecell junctioncellorganellemembrane-enclosed lumensupramolecular complexmembranecell junctioncellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumensupramolecular complexsupramolecular complexmembranemembranecell junctioncell junction
TypeGO IDTermEv.Code
 biological_processGO:0002159 desmosome assembly ISO
 biological_processGO:0002934 desmosome organization IBA
 biological_processGO:0007043 cell-cell junction assembly IBA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0009966 regulation of signal transduction IBA
 biological_processGO:0016264 gap junction assembly ISO
 biological_processGO:0030336 negative regulation of cell migration ISO
 biological_processGO:0034334 adherens junction maintenance ISO
 biological_processGO:0045110 intermediate filament bundle assembly ISO
 biological_processGO:0048496 maintenance of animal organ identity ISO
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis ISO
 biological_processGO:0055088 lipid homeostasis ISO
 biological_processGO:0072659 protein localization to plasma membrane ISO
 biological_processGO:0086001 cardiac muscle cell action potential ISO
 biological_processGO:0086002 cardiac muscle cell action potential involved in contraction ISO
 biological_processGO:0086005 ventricular cardiac muscle cell action potential ISO
 biological_processGO:0086019 cell-cell signaling involved in cardiac conduction ISO
 biological_processGO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication ISO
 biological_processGO:0086091 regulation of heart rate by cardiac conduction ISO
 biological_processGO:0098609 cell-cell adhesion IMP
 biological_processGO:0098911 regulation of ventricular cardiac muscle cell action potential ISO
 biological_processGO:2000810 regulation of bicellular tight junction assembly ISO
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005882 intermediate filament IDA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005912 adherens junction ISO
 cellular_componentGO:0005913 cell-cell adherens junction IBA
 cellular_componentGO:0014704 intercalated disc ISO
 cellular_componentGO:0030054 cell junction ISO
 cellular_componentGO:0030057 desmosome IDA
 molecular_functionGO:0005080 protein kinase C binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019215 intermediate filament binding ISO
 molecular_functionGO:0032947 protein-containing complex scaffold activity ISO
 molecular_functionGO:0045294 alpha-catenin binding ISO
 molecular_functionGO:0045296 cadherin binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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