675


Homo sapiens (NCBI)

Features
Gene ID: 675
  
Biological name :
  
Synonyms : BRCA2 / BRCA2, DNA repair associated / BRCC2|BROVCA2|FACD|FAD|FAD1|FANCD|FANCD1|GLM3|PNCA2|XRCC11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208368_s_at (Human Genome U133 Plus 2.0 Array)   214727_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 119395734
RefSeq - NC_000013.11
RefSeq - NG_012772.3
RefSeq - NP_000050.2
RefSeq - NM_000059.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000139618 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IDA
 biological_processGO:0000722 telomere maintenance via recombination IEA
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0001556 oocyte maturation IEA
 biological_processGO:0001833 inner cell mass cell proliferation IEA
 biological_processGO:0006289 nucleotide-excision repair IMP
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IEA
 biological_processGO:0007141 male meiosis I IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007569 cell aging IEA
 biological_processGO:0007584 response to nutrient IBA
 biological_processGO:0008585 female gonad development IEA
 biological_processGO:0010165 response to X-ray IEA
 biological_processGO:0010225 response to UV-C IEA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0010778 meiotic DNA repair synthesis involved in reciprocal meiotic recombination IBA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0030879 mammary gland development IBA
 biological_processGO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression IBA
 biological_processGO:0032355 response to estradiol IBA
 biological_processGO:0032465 regulation of cytokinesis IEA
 biological_processGO:0033600 negative regulation of mammary gland epithelial cell proliferation IDA
 biological_processGO:0035264 multicellular organism growth IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
 biological_processGO:0043150 DNA synthesis involved in double-strand break repair via homologous recombination IBA
 biological_processGO:0043966 histone H3 acetylation IDA
 biological_processGO:0043967 histone H4 acetylation IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045931 positive regulation of mitotic cell cycle IEA
 biological_processGO:0048478 replication fork protection IEA
 biological_processGO:0051298 centrosome duplication IMP
 biological_processGO:0051598 meiotic recombination checkpoint IBA
 biological_processGO:0070200 establishment of protein localization to telomere IDA
 biological_processGO:1990426 mitotic recombination-dependent replication fork processing IMP
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IDA
 cellular_componentGO:0000800 lateral element IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0030141 secretory granule IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0033593 BRCA2-MAGE-D1 complex IDA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0003697 single-stranded DNA binding IDA
 molecular_functionGO:0004402 histone acetyltransferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IDA
 molecular_functionGO:0010484 H3 histone acetyltransferase activity IDA
 molecular_functionGO:0010485 H4 histone acetyltransferase activity IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043015 gamma-tubulin binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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