6772


Homo sapiens (NCBI)

Features
Gene ID: 6772
  
Biological name :
  
Synonyms : CANDF7|IMD31A|IMD31B|IMD31C|ISGF-3|STAT91 / signal transducer and activator of transcription 1 / STAT1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 200887_s_at (Human Genome U133 Plus 2.0 Array)   209969_s_at (Human Genome U133 Plus 2.0 Array)   AFFX-HUMISGF3A/M97935_3_at (Human Genome U133 Plus 2.0 Array)   AFFX-HUMISGF3A/M97935_5_at (Human Genome U133 Plus 2.0 Array)   AFFX-HUMISGF3A/M97935_MA_at (Human Genome U133 Plus 2.0 Array)   AFFX-HUMISGF3A/M97935_MB_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034616158
RefSeq - 21536301
RefSeq - 578804821
RefSeq - 6274552
RefSeq - NC_000002.12
RefSeq - NG_008294.1
RefSeq - NP_009330.1
RefSeq - NP_644671.1
RefSeq - XP_006712781.1
RefSeq - XP_016860272.1
RefSeq - XM_006712718.1
RefSeq - XM_017004783.2
RefSeq - NM_007315.3
RefSeq - NM_139266.2
RefSeq - XR_001738914.2
RefSeq - XR_001738915.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000115415 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0001937 negative regulation of endothelial cell proliferation IMP
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation ISS
 biological_processGO:0002230 positive regulation of defense response to virus by host IMP
 biological_processGO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0007221 positive regulation of transcription of Notch receptor target TAS
 biological_processGO:0007259 JAK-STAT cascade IDA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0008015 blood circulation ISS
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0010742 macrophage derived foam cell differentiation IDA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016525 negative regulation of angiogenesis IMP
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0032727 positive regulation of interferon-alpha production IDA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IDA
 biological_processGO:0034097 response to cytokine ISS
 biological_processGO:0035456 response to interferon-beta IMP
 biological_processGO:0035458 cellular response to interferon-beta IMP
 biological_processGO:0038114 interleukin-21-mediated signaling pathway TAS
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0043434 response to peptide hormone ISS
 biological_processGO:0043542 endothelial cell migration IMP
 biological_processGO:0045648 positive regulation of erythrocyte differentiation IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0046725 negative regulation by virus of viral protein levels in host cell IMP
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISS
 biological_processGO:0051591 response to cAMP ISS
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0051770 positive regulation of nitric-oxide synthase biosynthetic process IEA
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway TAS
 biological_processGO:0060334 regulation of interferon-gamma-mediated signaling pathway TAS
 biological_processGO:0060337 type I interferon signaling pathway TAS
 biological_processGO:0061326 renal tubule development IMP
 biological_processGO:0070102 interleukin-6-mediated signaling pathway TAS
 biological_processGO:0070106 interleukin-27-mediated signaling pathway TAS
 biological_processGO:0070757 interleukin-35-mediated signaling pathway TAS
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 biological_processGO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development ISS
 biological_processGO:0072162 metanephric mesenchymal cell differentiation ISS
 biological_processGO:0072308 negative regulation of metanephric nephron tubule epithelial cell differentiation ISS
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0031730 CCR5 chemokine receptor binding IEA
 molecular_functionGO:0035035 histone acetyltransferase binding IPI
 molecular_functionGO:0035257 nuclear hormone receptor binding IPI
 molecular_functionGO:0042393 histone binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding IPI
 molecular_functionGO:0045296 cadherin binding HDA
 molecular_functionGO:0051721 protein phosphatase 2A binding IEA
 molecular_functionGO:0070491 repressing transcription factor binding IPI
 molecular_functionGO:1990841 promoter-specific chromatin binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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