6794


Homo sapiens (NCBI)

Features
Gene ID: 6794
  
Biological name :
  
Synonyms : LKB1|PJS|hLKB1 / serine/threonine kinase 11 / STK11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204292_x_at (Human Genome U133 Plus 2.0 Array)   231017_at (Human Genome U133 Plus 2.0 Array)   41657_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NC_000019.10
RefSeq - XP_005259674.1
RefSeq - XP_005259675.1
RefSeq - XP_011526511.1
RefSeq - NG_007460.2
RefSeq - 530425370
RefSeq - 4507271
RefSeq - NP_000446.1
RefSeq - 530425372
RefSeq - 768003611
RefSeq - XR_001753740.2
RefSeq - NM_000455.4
RefSeq - XM_005259617.3
RefSeq - XM_005259618.3
RefSeq - XM_011528209.2
RefSeq - XR_001753738.2
RefSeq - XR_001753739.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000118046 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth ISS
 biological_processGO:0001894 tissue homeostasis IEA
 biological_processGO:0001944 vasculature development ISS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0010212 response to ionizing radiation ISS
 biological_processGO:0010508 positive regulation of autophagy IMP
 biological_processGO:0030010 establishment of cell polarity ISS
 biological_processGO:0030111 regulation of Wnt signaling pathway IEA
 biological_processGO:0030308 negative regulation of cell growth ISS
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0036399 TCR signalosome assembly IEA
 biological_processGO:0042593 glucose homeostasis ISS
 biological_processGO:0043276 anoikis IMP
 biological_processGO:0045059 positive thymic T cell selection IEA
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048814 regulation of dendrite morphogenesis IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0050772 positive regulation of axonogenesis IEA
 biological_processGO:0050852 T cell receptor signaling pathway IEA
 biological_processGO:0051055 negative regulation of lipid biosynthetic process IEA
 biological_processGO:0051645 Golgi localization IEA
 biological_processGO:0051896 regulation of protein kinase B signaling IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development IEA
 biological_processGO:0071493 cellular response to UV-B IDA
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IDA
 biological_processGO:0097484 dendrite extension IEA
 biological_processGO:1900182 positive regulation of protein localization to nucleus IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 biological_processGO:1904262 negative regulation of TORC1 signaling IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0036398 TCR signalosome IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0002039 p53 binding IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0030275 LRR domain binding IEA
 molecular_functionGO:0030295 protein kinase activator activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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