6850


Homo sapiens (NCBI)

Features
Gene ID: 6850
  
Biological name :
  
Synonyms : p72-Syk / spleen associated tyrosine kinase / SYK
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207540_s_at (Human Genome U133 Plus 2.0 Array)   209269_s_at (Human Genome U133 Plus 2.0 Array)   226068_at (Human Genome U133 Plus 2.0 Array)   244023_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001167639.1
RefSeq - NP_003168.2
RefSeq - 767958118
RefSeq - NC_000009.12
RefSeq - XP_005252204.1
RefSeq - XP_011517248.1
RefSeq - 205277435
RefSeq - NG_017046.1
RefSeq - 21361553
RefSeq - 293332585
RefSeq - 293332611
RefSeq - 530391443
RefSeq - NP_001128524.1
RefSeq - NP_001167638.1
RefSeq - XR_001746370.2
RefSeq - NM_001135052.3
RefSeq - NM_001174167.2
RefSeq - NM_001174168.2
RefSeq - NM_003177.6
RefSeq - XM_005252147.4
RefSeq - XM_011518946.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000165025 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001945 lymph vessel development ISS
 biological_processGO:0002092 positive regulation of receptor internalization IEA
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0002250 adaptive immune response ISS
 biological_processGO:0002281 macrophage activation involved in immune response ISS
 biological_processGO:0002283 neutrophil activation involved in immune response ISS
 biological_processGO:0002366 leukocyte activation involved in immune response ISS
 biological_processGO:0002554 serotonin secretion by platelet ISS
 biological_processGO:0006468 protein phosphorylation ISS
 biological_processGO:0006606 protein import into nucleus IMP
 biological_processGO:0007159 leukocyte cell-cell adhesion IDA
 biological_processGO:0007229 integrin-mediated signaling pathway NAS
 biological_processGO:0007257 activation of JUN kinase activity IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0009887 animal organ morphogenesis TAS
 biological_processGO:0010543 regulation of platelet activation ISS
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway IMP
 biological_processGO:0016032 viral process IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0019370 leukotriene biosynthetic process IEA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030593 neutrophil chemotaxis IDA
 biological_processGO:0031623 receptor internalization ISS
 biological_processGO:0032481 positive regulation of type I interferon production IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production ISS
 biological_processGO:0032928 regulation of superoxide anion generation ISS
 biological_processGO:0033630 positive regulation of cell adhesion mediated by integrin ISS
 biological_processGO:0038063 collagen-activated tyrosine kinase receptor signaling pathway IEA
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0038110 interleukin-2-mediated signaling pathway TAS
 biological_processGO:0038156 interleukin-3-mediated signaling pathway ISS
 biological_processGO:0042742 defense response to bacterium ISS
 biological_processGO:0043306 positive regulation of mast cell degranulation IBA
 biological_processGO:0043313 regulation of neutrophil degranulation ISS
 biological_processGO:0043366 beta selection IEA
 biological_processGO:0045087 innate immune response ISS
 biological_processGO:0045401 positive regulation of interleukin-3 biosynthetic process IEA
 biological_processGO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process IEA
 biological_processGO:0045579 positive regulation of B cell differentiation IMP
 biological_processGO:0045588 positive regulation of gamma-delta T cell differentiation IEA
 biological_processGO:0045780 positive regulation of bone resorption ISS
 biological_processGO:0046638 positive regulation of alpha-beta T cell differentiation IEA
 biological_processGO:0046641 positive regulation of alpha-beta T cell proliferation IBA
 biological_processGO:0048514 blood vessel morphogenesis ISS
 biological_processGO:0050715 positive regulation of cytokine secretion IEA
 biological_processGO:0050764 regulation of phagocytosis ISS
 biological_processGO:0050850 positive regulation of calcium-mediated signaling IEA
 biological_processGO:0050853 B cell receptor signaling pathway ISS
 biological_processGO:0051090 regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0071226 cellular response to molecule of fungal origin ISS
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus ISS
 biological_processGO:0090237 regulation of arachidonic acid secretion ISS
 biological_processGO:0090330 regulation of platelet aggregation ISS
 biological_processGO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0019815 B cell receptor complex IEA
 cellular_componentGO:0032009 early phagosome ISS
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0042101 T cell receptor complex IDA
 molecular_functionGO:0001784 phosphotyrosine residue binding IPI
 molecular_functionGO:0004672 protein kinase activity NAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity TAS
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019902 phosphatase binding IEA
 molecular_functionGO:0035325 Toll-like receptor binding IEA
 molecular_functionGO:0042169 SH2 domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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