6868


Homo sapiens (NCBI)

Features
Gene ID: 6868
  
Biological name :
  
Synonyms : ADAM17 / ADAM18|CD156B|CSVP|NISBD|NISBD1|TACE / ADAM metallopeptidase domain 17
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205745_x_at (Human Genome U133 Plus 2.0 Array)   205746_s_at (Human Genome U133 Plus 2.0 Array)   213532_at (Human Genome U133 Plus 2.0 Array)   237897_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034616171
RefSeq - 1034616173
RefSeq - 1370478690
RefSeq - 73747889
RefSeq - 767913304
RefSeq - 767913306
RefSeq - NC_000002.12
RefSeq - NG_029873.1
RefSeq - NP_003174.3
RefSeq - XP_011508677.1
RefSeq - XP_011508678.1
RefSeq - XP_016860274.1
RefSeq - XP_016860275.1
RefSeq - XP_024308824.1
RefSeq - NM_003183.6
RefSeq - XM_024453056.1
RefSeq - XM_011510375.3
RefSeq - XM_011510376.3
RefSeq - XM_017004785.2
RefSeq - XM_017004786.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000151694 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0002446 neutrophil mediated immunity IC
 biological_processGO:0002467 germinal center formation ISS
 biological_processGO:0002690 positive regulation of leukocyte chemotaxis IC
 biological_processGO:0006508 proteolysis IDA
 biological_processGO:0006509 membrane protein ectodomain proteolysis IMP
 biological_processGO:0007155 cell adhesion IDA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IDA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007220 Notch receptor processing IDA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010820 positive regulation of T cell chemotaxis IMP
 biological_processGO:0030183 B cell differentiation ISS
 biological_processGO:0030307 positive regulation of cell growth IMP
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway ISS
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0031293 membrane protein intracellular domain proteolysis TAS
 biological_processGO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle IDA
 biological_processGO:0032496 response to lipopolysaccharide IDA
 biological_processGO:0032722 positive regulation of chemokine production IMP
 biological_processGO:0033025 regulation of mast cell apoptotic process ISS
 biological_processGO:0033077 T cell differentiation in thymus ISS
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0033627 cell adhesion mediated by integrin IDA
 biological_processGO:0035313 wound healing, spreading of epidermal cells IEP
 biological_processGO:0042493 response to drug ISS
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IDA
 biological_processGO:0045741 positive regulation of epidermal growth factor-activated receptor activity IMP
 biological_processGO:0048536 spleen development ISS
 biological_processGO:0048870 cell motility ISS
 biological_processGO:0050830 defense response to Gram-positive bacterium IMP
 biological_processGO:0051088 PMA-inducible membrane protein ectodomain proteolysis IMP
 biological_processGO:0051272 positive regulation of cellular component movement ISS
 biological_processGO:0071403 cellular response to high density lipoprotein particle stimulus IDA
 biological_processGO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway IMP
 biological_processGO:1905564 positive regulation of vascular endothelial cell proliferation IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0032587 ruffle membrane IDA
 cellular_componentGO:0045121 membrane raft IDA
 molecular_functionGO:0004222 metalloendopeptidase activity TAS
 molecular_functionGO:0005112 Notch binding IDA
 molecular_functionGO:0005138 interleukin-6 receptor binding IPI
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008237 metallopeptidase activity TAS
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0030165 PDZ domain binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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