7010


Homo sapiens (NCBI)

Features
Gene ID: 7010
  
Biological name :
  
Synonyms : CD202B|GLC3E|TIE-2|TIE2|VMCM|VMCM1 / TEK / TEK receptor tyrosine kinase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206702_at (Human Genome U133 Plus 2.0 Array)   217711_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 530390107
RefSeq - 530390111
RefSeq - 587651917
RefSeq - 587651919
RefSeq - 88758596
RefSeq - NC_000009.12
RefSeq - NG_011828.1
RefSeq - NP_000450.2
RefSeq - NP_001277006.1
RefSeq - NP_001277007.1
RefSeq - XP_005251618.1
RefSeq - XP_005251620.1
RefSeq - NM_000459.4
RefSeq - NM_001290077.1
RefSeq - NM_001290078.1
RefSeq - XM_005251563.2
RefSeq - XM_005251561.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000120156 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001525 angiogenesis ISS
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0001935 endothelial cell proliferation ISS
 biological_processGO:0001938 positive regulation of endothelial cell proliferation TAS
 biological_processGO:0001958 endochondral ossification IEA
 biological_processGO:0002040 sprouting angiogenesis IMP
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IDA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007507 heart development ISS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010595 positive regulation of endothelial cell migration IMP
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IMP
 biological_processGO:0016525 negative regulation of angiogenesis IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0032878 regulation of establishment or maintenance of cell polarity IMP
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IMP
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043114 regulation of vascular permeability TAS
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IMP
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048014 Tie signaling pathway IDA
 biological_processGO:0050728 negative regulation of inflammatory response TAS
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051259 protein complex oligomerization IDA
 biological_processGO:0051591 response to cAMP IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IMP
 biological_processGO:0051897 positive regulation of protein kinase B signaling IMP
 biological_processGO:0060216 definitive hemopoiesis TAS
 biological_processGO:0060347 heart trabecula formation ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0072012 glomerulus vasculature development ISS
 biological_processGO:1902533 positive regulation of intracellular signal transduction IMP
 biological_processGO:2000251 positive regulation of actin cytoskeleton reorganization IMP
 biological_processGO:2000351 regulation of endothelial cell apoptotic process TAS
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process ISS
 cellular_componentGO:0001725 stress fiber IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005884 actin filament IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005902 microvillus IDA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0009925 basal plasma membrane IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0045121 membrane raft IDA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019838 growth factor binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038023 signaling receptor activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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