7186


Homo sapiens (NCBI)

Features
Gene ID: 7186
  
Biological name :
  
Synonyms : MGC:45012|RNF117|TRAP|TRAP3 / TNF receptor associated factor 2 / TRAF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204413_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_011517279.1
RefSeq - 767958178
RefSeq - 767958182
RefSeq - 767958184
RefSeq - NC_000009.12
RefSeq - NP_066961.2
RefSeq - XP_011517276.1
RefSeq - XP_011517278.1
RefSeq - 22027612
RefSeq - NM_021138.3
RefSeq - XM_011518977.2
RefSeq - XM_011518974.2
RefSeq - XM_011518976.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000127191 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002726 positive regulation of T cell cytokine production IMP
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity IMP
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0030163 protein catabolic process IEA
 biological_processGO:0032743 positive regulation of interleukin-2 production IMP
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0034351 negative regulation of glial cell apoptotic process IEA
 biological_processGO:0034622 cellular protein-containing complex assembly ISS
 biological_processGO:0034976 response to endoplasmic reticulum stress NAS
 biological_processGO:0042981 regulation of apoptotic process IDA
 biological_processGO:0043507 positive regulation of JUN kinase activity IDA
 biological_processGO:0051023 regulation of immunoglobulin secretion IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:0051865 protein autoubiquitination TAS
 biological_processGO:0065003 protein-containing complex assembly TAS
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress TAS
 biological_processGO:0070207 protein homotrimerization IPI
 biological_processGO:0070534 protein K63-linked ubiquitination IDA
 biological_processGO:0071550 death-inducing signaling complex assembly TAS
 biological_processGO:0071732 cellular response to nitric oxide IEA
 biological_processGO:0090073 positive regulation of protein homodimerization activity IMP
 biological_processGO:0097300 programmed necrotic cell death IEA
 biological_processGO:1901215 negative regulation of neuron death TAS
 biological_processGO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors TAS
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors TAS
 biological_processGO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:1903721 positive regulation of I-kappaB phosphorylation IEA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0000151 ubiquitin ligase complex IPI
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0012506 vesicle membrane IEA
 cellular_componentGO:0035631 CD40 receptor complex ISS
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0097057 TRAF2-GSTP1 complex IDA
 cellular_componentGO:1990597 AIP1-IRE1 complex IEA
 cellular_componentGO:1990604 IRE1-TRAF2-ASK1 complex IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IPI
 molecular_functionGO:0005174 CD40 receptor binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0031996 thioesterase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0046625 sphingolipid binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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