7189


Homo sapiens (NCBI)

Features
Gene ID: 7189
  
Biological name :
  
Synonyms : MGC:3310|RNF85 / TNF receptor associated factor 6 / TRAF6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205558_at (Human Genome U133 Plus 2.0 Array)   227264_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034575177
RefSeq - 22027630
RefSeq - 4759254
RefSeq - NC_000011.10
RefSeq - NP_004611.1
RefSeq - NP_665802.1
RefSeq - XP_016873709.1
RefSeq - NM_004620.3
RefSeq - NM_145803.2
RefSeq - XM_017018220.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000175104 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0001503 ossification IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0002224 toll-like receptor signaling pathway TAS
 biological_processGO:0002726 positive regulation of T cell cytokine production IMP
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity IMP
 biological_processGO:0007254 JNK cascade TAS
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II IEA
 biological_processGO:0030316 osteoclast differentiation IEA
 biological_processGO:0031293 membrane protein intracellular domain proteolysis TAS
 biological_processGO:0031398 positive regulation of protein ubiquitination NAS
 biological_processGO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032147 activation of protein kinase activity IDA
 biological_processGO:0032743 positive regulation of interleukin-2 production IMP
 biological_processGO:0034162 toll-like receptor 9 signaling pathway TAS
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0042088 T-helper 1 type immune response IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0043011 myeloid dendritic cell differentiation IEA
 biological_processGO:0043065 positive regulation of apoptotic process TAS
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0043507 positive regulation of JUN kinase activity NAS
 biological_processGO:0045084 positive regulation of interleukin-12 biosynthetic process IEA
 biological_processGO:0045410 positive regulation of interleukin-6 biosynthetic process IEA
 biological_processGO:0045453 bone resorption IEA
 biological_processGO:0045672 positive regulation of osteoclast differentiation IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II NAS
 biological_processGO:0048468 cell development IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0051023 regulation of immunoglobulin secretion IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity TAS
 biological_processGO:0051865 protein autoubiquitination TAS
 biological_processGO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS
 biological_processGO:0070498 interleukin-1-mediated signaling pathway TAS
 biological_processGO:0070534 protein K63-linked ubiquitination IGI
 biological_processGO:0070555 response to interleukin-1 IDA
 biological_processGO:0071222 cellular response to lipopolysaccharide IDA
 biological_processGO:2000679 positive regulation of transcription regulatory region DNA binding IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005811 lipid droplet ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0035631 CD40 receptor complex ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding IPI
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0031996 thioesterase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0043422 protein kinase B binding IPI
 molecular_functionGO:0047485 protein N-terminus binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr