7345


Homo sapiens (NCBI)
activityproteinbindingaxonbehaviorcellregulationprocesscytoplasmmembranethiol-dependentligaseubiquitinresponseischemiatargetrecognitionadultwalkingproliferationmacroautophagydeubiquitinationsensoryperceptionpainaxonaltransportmitochondrioneatingproteasome-mediated

Features
Gene ID: 7345
  
Biological name :
  
Synonyms : HEL-117|HEL-S-53|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|SPG79|Uch-L1 / ubiquitin C-terminal hydrolase L1 / UCHL1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1555834_at (Human Genome U133 Plus 2.0 Array)   201387_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 21361091
RefSeq - NC_000004.12
RefSeq - NG_012931.1
RefSeq - NP_004172.2
RefSeq - NM_004181.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000154277 to get all the annotations available for this gene.


Gene Ontology (GO)
response to stresscell communicationcellular component organizationanatomical structure developmentcellular developmental processlocomotory behavioradult behaviorcatabolic processcellular metabolic processprocess utilizing autophagic mechanismnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processsystem processestablishment of localizationmovement of cell or subcellular componentcellular localizationmicrotubule-based processfeeding behaviorregulation of molecular functioncellular response to stimulusresponse to stresscell communicationcellular component organizationanatomical structure developmentcellular developmental processlocomotory behavioradult behaviorcatabolic processcellular metabolic processprocess utilizing autophagic mechanismnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processsystem processestablishment of localizationmovement of cell or subcellular componentcellular localizationmicrotubule-based processfeeding behaviorregulation of molecular functioncellular response to stimulusresponse to stresscell communicationcellular component organizationanatomical structure developmentcellular developmental processlocomotory behavioradult behaviorcatabolic processcellular metabolic processprocess utilizing autophagic mechanismnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processsystem processestablishment of localizationmovement of cell or subcellular componentcellular localizationmicrotubule-based processfeeding behaviorregulation of molecular functioncellular response to stimulusresponse to stresscell communicationcellular component organizationanatomical structure developmentcellular developmental processlocomotory behavioradult behaviorcatabolic processcellular metabolic processprocess utilizing autophagic mechanismnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processsystem processestablishment of localizationmovement of cell or subcellular componentcellular localizationmicrotubule-based processfeeding behaviorregulation of molecular functioncellular response to stimulusresponse to stresscell communicationcellular component organizationanatomical structure developmentcellular developmental processlocomotory behavioradult behaviorcatabolic processcellular metabolic processprocess utilizing autophagic mechanismnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processsystem processestablishment of localizationmovement of cell or subcellular componentcellular localizationmicrotubule-based processfeeding behaviorregulation of molecular functioncellular response to stimulusresponse to stresscell communicationcellular component organizationanatomical structure developmentcellular developmental processlocomotory behavioradult behaviorcatabolic processcellular metabolic processprocess utilizing autophagic mechanismnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processsystem processestablishment of localizationmovement of cell or subcellular componentcellular localizationmicrotubule-based processfeeding behaviorregulation of molecular functioncellular response to stimulusresponse to stresscell communicationcellular component organizationanatomical structure developmentcellular developmental processlocomotory behavioradult behaviorcatabolic processcellular metabolic processprocess utilizing autophagic mechanismnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processsystem processestablishment of localizationmovement of cell or subcellular componentcellular localizationmicrotubule-based processfeeding behaviorregulation of molecular functioncellular response to stimulusresponse to stresscell communicationcellular component organizationanatomical structure developmentcellular developmental processlocomotory behavioradult behaviorcatabolic processcellular metabolic processprocess utilizing autophagic mechanismnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processsystem processestablishment of localizationmovement of cell or subcellular componentcellular localizationmicrotubule-based processfeeding behaviorregulation of molecular functioncellular response to stimulusresponse to stresscell communicationcellular component organizationanatomical structure developmentcellular developmental processlocomotory behavioradult behaviorcatabolic processcellular metabolic processprocess utilizing autophagic mechanismnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processsystem processestablishment of localizationmovement of cell or subcellular componentcellular localizationmicrotubule-based processfeeding behaviorregulation of molecular functioncellular response to stimulusresponse to stresscell communicationcellular component organizationanatomical structure developmentcellular developmental processlocomotory behavioradult behaviorcatabolic processcellular metabolic processprocess utilizing autophagic mechanismnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processsystem processestablishment of localizationmovement of cell or subcellular componentcellular localizationmicrotubule-based processfeeding behaviorregulation of molecular functioncellular response to stimulusresponresponse to stresscell ccell communicationcellulcellular component organizationanatomanatomical structure developmentcellulcellular developmental processlocomolocomotory behavioradult adult behaviorcatabocatabolic processcellulcellular metabolic processprocesprocess utilizing autophagic mechanismnitrognitrogen compound metabolic processprimarprimary metabolic processorganiorganic substance metabolic processsystemsystem processestablestablishment of localizationmovememovement of cell or subcellular componentcellulcellular localizationmicrotmicrotubule-based processfeedinfeeding behaviorregularegulation of molecular functioncellulcellular response to stimulus
catalytic activity, acting on a proteinhydrolase activityprotein bindingligase activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingligase activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingligase activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingligase activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingligase activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingligase activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingligase activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingligase activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingligase activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingligase activitycatalytic activity, acting on a procatalytic activity, acting on a proteinhydrolase activityhydrolase activityprotein bindingprotein bindingligase activityligase activity
cellorganellemembrane-enclosed lumenmembranecellorganellemembrane-enclosed lumenmembranecellorganellemembrane-enclosed lumenmembranecellorganellemembrane-enclosed lumenmembranecellorganellemembrane-enclosed lumenmembranecellorganellemembrane-enclosed lumenmembranecellorganellemembrane-enclosed lumenmembranecellorganellemembrane-enclosed lumenmembranecellorganellemembrane-enclosed lumenmembranecellorganellemembrane-enclosed lumenmembranecellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0002931 response to ischemia IEA
 biological_processGO:0007412 axon target recognition IEA
 biological_processGO:0007628 adult walking behavior IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0019896 axonal transport of mitochondrion IEA
 biological_processGO:0042755 eating behavior IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process NAS
 biological_processGO:0043407 negative regulation of MAP kinase activity IDA
 biological_processGO:0048747 muscle fiber development IEA
 biological_processGO:0050905 neuromuscular process IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0044306 neuron projection terminus IEA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IDA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008242 omega peptidase activity IDA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0031694 alpha-2A adrenergic receptor binding IPI
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity TAS
 molecular_functionGO:0043130 ubiquitin binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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