7421


Homo sapiens (NCBI)

Features
Gene ID: 7421
  
Biological name :
  
Synonyms : NR1I1|PPP1R163 / VDR / vitamin D receptor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204253_s_at (Human Genome U133 Plus 2.0 Array)   204254_s_at (Human Genome U133 Plus 2.0 Array)   204255_s_at (Human Genome U133 Plus 2.0 Array)   213692_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1370462775
RefSeq - 1395955162
RefSeq - 323714265
RefSeq - 4507883
RefSeq - 578824200
RefSeq - 63054845
RefSeq - 767975260
RefSeq - NC_000012.12
RefSeq - NG_008731.1
RefSeq - NP_000367.1
RefSeq - NP_001017535.1
RefSeq - NP_001017536.1
RefSeq - NP_001351014.1
RefSeq - XP_006719650.1
RefSeq - XP_011537022.1
RefSeq - XP_024304946.1
RefSeq - NM_000376.2
RefSeq - NM_001017535.1
RefSeq - NM_001017536.1
RefSeq - NM_001364085.1
RefSeq - XM_024449178.1
RefSeq - XM_006719587.3
RefSeq - XM_011538720.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000111424 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0000902 cell morphogenesis IMP
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007595 lactation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0009887 animal organ morphogenesis IBA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010839 negative regulation of keratinocyte proliferation IMP
 biological_processGO:0010980 positive regulation of vitamin D 24-hydroxylase activity IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0038183 bile acid signaling pathway IDA
 biological_processGO:0042359 vitamin D metabolic process TAS
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045618 positive regulation of keratinocyte differentiation IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0046697 decidualization IEP
 biological_processGO:0050892 intestinal absorption IEA
 biological_processGO:0060058 positive regulation of apoptotic process involved in mammary gland involution IEA
 biological_processGO:0060429 epithelium development IBA
 biological_processGO:0060558 regulation of calcidiol 1-monooxygenase activity ISS
 biological_processGO:0060745 mammary gland branching involved in pregnancy IEA
 biological_processGO:0070561 vitamin D receptor signaling pathway IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IDA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IBA
 molecular_functionGO:0005499 vitamin D binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IBA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0008434 calcitriol receptor activity IMP
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IBA
 molecular_functionGO:0038186 lithocholic acid receptor activity IDA
 molecular_functionGO:0046965 retinoid X receptor binding IPI
 molecular_functionGO:0070644 vitamin D response element binding IDA
 molecular_functionGO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding IBA
 molecular_functionGO:1902098 calcitriol binding IMP
 molecular_functionGO:1902121 lithocholic acid binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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