7454


Homo sapiens (NCBI)

Features
Gene ID: 7454
  
Biological name :
  
Synonyms : IMD2|SCNX|THC|THC1|WASP|WASPA / WAS / Wiskott-Aldrich syndrome
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205400_at (Human Genome U133 Plus 2.0 Array)   38964_r_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034675132
RefSeq - 4507909
RefSeq - 768033853
RefSeq - NC_000023.11
RefSeq - NG_007877.1
RefSeq - NP_000368.1
RefSeq - XP_011542279.1
RefSeq - XP_016885275.1
RefSeq - NM_000377.2
RefSeq - XM_017029786.1
RefSeq - XM_011543977.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000015285 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000147 actin cortical patch assembly IBA
 biological_processGO:0002625 regulation of T cell antigen processing and presentation IMP
 biological_processGO:0006897 endocytosis IBA
 biological_processGO:0006952 defense response TAS
 biological_processGO:0006955 immune response IMP
 biological_processGO:0007266 Rho protein signal transduction IMP
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0008064 regulation of actin polymerization or depolymerization IMP
 biological_processGO:0008154 actin polymerization or depolymerization TAS
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0008544 epidermis development TAS
 biological_processGO:0010591 regulation of lamellipodium assembly IGI
 biological_processGO:0016197 endosomal transport IEA
 biological_processGO:0030041 actin filament polymerization IEA
 biological_processGO:0030048 actin filament-based movement IEA
 biological_processGO:0032488 Cdc42 protein signal transduction IMP
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0042110 T cell activation IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0051127 positive regulation of actin nucleation IBA
 biological_processGO:0051492 regulation of stress fiber assembly IGI
 biological_processGO:0051497 negative regulation of stress fiber assembly IMP
 biological_processGO:0051666 actin cortical patch localization IBA
 biological_processGO:0065003 protein-containing complex assembly TAS
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 biological_processGO:2000146 negative regulation of cell motility IMP
 biological_processGO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005884 actin filament IDA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0012506 vesicle membrane IEA
 cellular_componentGO:0015629 actin cytoskeleton TAS
 cellular_componentGO:0030479 actin cortical patch IBA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0030695 GTPase regulator activity TAS
 molecular_functionGO:0031267 small GTPase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043274 phospholipase binding IPI
 molecular_functionGO:0048365 Rac GTPase binding IPI
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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