841


Homo sapiens (NCBI)

Features
Gene ID: 841
  
Biological name :
  
Synonyms : ALPS2B|CAP4|Casp-8|FLICE|MACH|MCH5 / CASP8 / caspase 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1553306_at (Human Genome U133 Plus 2.0 Array)   207686_s_at (Human Genome U133 Plus 2.0 Array)   213373_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 530371045
RefSeq - 122056476
RefSeq - 15718704
RefSeq - 15718706
RefSeq - 15718708
RefSeq - 15718712
RefSeq - 530371024
RefSeq - 530371026
RefSeq - 530371028
RefSeq - 530371030
RefSeq - 530371032
RefSeq - 530371034
RefSeq - 530371036
RefSeq - 530371038
RefSeq - 530371041
RefSeq - 530371043
RefSeq - 122056474
RefSeq - 578804998
RefSeq - 578805001
RefSeq - 578805007
RefSeq - 767920069
RefSeq - NC_000002.12
RefSeq - NG_007497.1
RefSeq - NP_001073593.1
RefSeq - NP_001073594.1
RefSeq - NP_001219.2
RefSeq - NP_203519.1
RefSeq - NP_203520.1
RefSeq - NP_203522.1
RefSeq - XP_005246942.1
RefSeq - XP_005246943.1
RefSeq - XP_005246944.1
RefSeq - XP_005246945.1
RefSeq - XP_005246946.1
RefSeq - XP_005246947.1
RefSeq - XP_005246948.1
RefSeq - XP_005246949.1
RefSeq - XP_005246950.1
RefSeq - XP_005246951.1
RefSeq - XP_005246952.1
RefSeq - XP_006712852.1
RefSeq - XP_006712853.1
RefSeq - XP_006712856.1
RefSeq - XP_011510271.1
RefSeq - XM_005246892.2
RefSeq - XM_005246893.3
RefSeq - XM_005246894.4
RefSeq - XM_005246895.3
RefSeq - NM_001080124.1
RefSeq - NM_001080125.1
RefSeq - NM_001228.4
RefSeq - NM_033355.3
RefSeq - NM_033356.3
RefSeq - NM_033357.2
RefSeq - NM_033358.3
RefSeq - XM_006712789.2
RefSeq - XM_006712790.4
RefSeq - XM_006712793.3
RefSeq - XM_011511969.2
RefSeq - XR_923035.1
RefSeq - XR_001738971.1
RefSeq - NR_111983.1
RefSeq - XM_005246885.2
RefSeq - XM_005246886.2
RefSeq - XM_005246887.2
RefSeq - XM_005246888.2
RefSeq - XM_005246889.2
RefSeq - XM_005246890.4
RefSeq - XM_005246891.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000064012 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IDA
 biological_processGO:0006915 apoptotic process IMP
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IBA
 biological_processGO:0009409 response to cold IEA
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0030101 natural killer cell activation TAS
 biological_processGO:0030225 macrophage differentiation TAS
 biological_processGO:0032025 response to cobalt ion IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0034138 toll-like receptor 3 signaling pathway TAS
 biological_processGO:0034612 response to tumor necrosis factor IMP
 biological_processGO:0035666 TRIF-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0036462 TRAIL-activated apoptotic signaling pathway IDA
 biological_processGO:0039650 suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process TAS
 biological_processGO:0042110 T cell activation TAS
 biological_processGO:0042113 B cell activation TAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045651 positive regulation of macrophage differentiation IMP
 biological_processGO:0045862 positive regulation of proteolysis IDA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IMP
 biological_processGO:0060544 regulation of necroptotic process TAS
 biological_processGO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development TAS
 biological_processGO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS
 biological_processGO:0071260 cellular response to mechanical stimulus IEP
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 biological_processGO:0071550 death-inducing signaling complex assembly TAS
 biological_processGO:0097190 apoptotic signaling pathway TAS
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IDA
 biological_processGO:0097194 execution phase of apoptosis TAS
 biological_processGO:0097202 activation of cysteine-type endopeptidase activity IDA
 biological_processGO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway TAS
 biological_processGO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway TAS
 biological_processGO:1901216 positive regulation of neuron death IEA
 biological_processGO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors TAS
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0031264 death-inducing signaling complex IDA
 cellular_componentGO:0031265 CD95 death-inducing signaling complex IDA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0044297 cell body IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0097342 ripoptosome IDA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity TAS
 molecular_functionGO:0005123 death receptor binding IEA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IMP
 molecular_functionGO:0008234 cysteine-type peptidase activity TAS
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0035877 death effector domain binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0097110 scaffold protein binding IPI
 molecular_functionGO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IMP
 molecular_functionGO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway IMP
 molecular_functionGO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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