84504


Homo sapiens (NCBI)
regulationtranscriptionrnapolymeraseiicellpromoterdnabindingfatesequence-specificactivitydna-templatedcommitmentinvolvedspinalcordspecificationmyelinationglialdifferentiationproximalfactormotorneuronventralinterneuroncentralnervousendocrine

Features
Gene ID: 84504
  
Biological name :
  
Synonyms : GTX|NKX6.2|NKX6B|SPAX8 / NK6 homeobox 2 / NKX6-2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 235832_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 28912912
RefSeq - XP_016872278.1
RefSeq - NC_000010.11
RefSeq - 1034569965
RefSeq - NP_796374.1
RefSeq - NM_177400.2
RefSeq - XM_017016789.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000148826 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular developmental processanatomical structure developmentsystem processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular developmental processanatomical structure developmentsystem processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular developmental processanatomical structure developmentsystem processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular developmental processanatomical structure developmentsystem processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular developmental processanatomical structure developmentsystem processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular developmental processanatomical structure developmentsystem processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular developmental processanatomical structure developmentsystem processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular developmental processanatomical structure developmentsystem processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular developmental processanatomical structure developmentsystem processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular developmental processanatomical structure developmentsystem processnitrogen compoundnitrogen compound metabolic processbiosynthetic procbiosynthetic processcellular metabolicellular metabolic processprimary metabolicprimary metabolic processorganic substanceorganic substance metabolic processcellular developmcellular developmental processanatomical structanatomical structure developmentsystem processsystem process
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityDNA-binding transcription factor activity
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0010454 negative regulation of cell fate commitment IEA
 biological_processGO:0010455 positive regulation of cell fate commitment IEA
 biological_processGO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification IEA
 biological_processGO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification IEA
 biological_processGO:0022010 central nervous system myelination IEA
 biological_processGO:0031018 endocrine pancreas development IEA
 biological_processGO:0031641 regulation of myelination ISS
 biological_processGO:0045686 negative regulation of glial cell differentiation IEA
 biological_processGO:0045687 positive regulation of glial cell differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0050885 neuromuscular process controlling balance IEA
 cellular_componentGO:0005634 nucleus NAS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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